عودة

 

الدكتور / محمود فهمى علي الصبحي
مدير مركز أسيوط الدولى لأدوية النانو بمستشفى الراجحى للكبد، جامعة أسيوط
أستاذ مساعد بقسم الصيدلانيات، كلية الصيدلة، جامعة أسيوط
تفاصيل السيرة الذاتية
بيانات ال MIS دخول الإعضاء تواصل مع العضو نسخة للطباعة
العنوان الحالى قسم الصيدلانيات - كلية الصيدلة - جامعة أسيوط - أسيوط - مصر
الموبايل 01005669011
تليفون المنزل 0020882296767
الفاكس +20882080774
البريد الالكترونى mahmoud.elsoubhi@pharm.aun.edu.eg
mfsabahy@yahoo.com
google scholar link http://scholar.google.com.eg/citations?user=Ceu2gy0AAAAJ&hl=en
  • دكتوراه فى العلوم الصيدلية ( الصيدلانيات ) ، جامعة مونتريال ، كندا، 2010
  • بكالوريوس فى العلوم الصيدلية، كلية الصيدلة، جامعة أسيوط، 2003
الدرجات العلمية :
  • أستاذ مساعد بقسم الصيدلانيات، كلية الصيدلة، جامعة أسيوط، 2015
  • مدرس بقسم الصيدلانيات، كلية الصيدلة، جامعة أسيوط، 2010
  • معيد بقسم الصيدلانيات، كلية الصيدلة، جامعة أسيوط، 2003
المناصب الادارية :
المنصب الحالى :
مدير مركز أسيوط الدولى لأدوية النانو بمستشفى الراجحى للكبد، جامعة أسيوط, منذ 09-2012
المناصب السابقة :
نائب مدير مركز بحوث الدواء، جامعة أسيوط, في الفترة من (11-2013 إلى 05-2018 )

المجالات البحثية:
nanotechnology

الابحاث :

1-Safy Hadiya, Xiaoqiang Liu, Wegdan Abd El-Hammed, Mahmoud Elsabahy, Sherine A Aly , Levofloxacin-Loaded Nanoparticles Decrease Emergence of Fluoroquinolone Resistance in Escherichia coli, Microbial Drug Resistance, https://doi.org/10.1089/mdr.2017.0304, February, 2018
2-Heba A. Fathi, Ayat Allam, Mahmoud Elsabahy, Gihan Fetih and Mahmoud El-Badry, Nanostructured Lipid Carriers for Improved Oral Delivery and Prolonged Antihyperlipidemic Effect of Simvastatin, Colloids and Surfaces B: Biointerfaces, Vol. 162, pp. 236-245, https://doi.org/10.1016/j.colsurfb.2017.11.064, 2018
3-Helmy A.M., Elsabahy M., Soliman G.M., Mahmoud M.A. and Ibrahim E.A, Development and In Vivo Evaluation of Chitosan Beads for the Colonic Delivery of Azathioprine for Treatment of Inflammatory Bowel Disease, Eur. J. Pharm. Sci., DOI: 10.1016/j.ejps.2017.08.025, Vol. 109, pp. 269-279, 2017
4-Fuwu Zhang, Shiyi Zhang, Stephanie F. Pollack, Richen Li, Amelia M. Gonzalez, Jingwei Fan, Jiong Zou, Sarah E. Leininger, Adriana Pavía-Sanders, Rachel Johnson, Laura D. Nelson, Jeffery E. Raymond, Mahmoud Elsabahy, Dennis M. P. Hughes, Mark W. Lenox, Tiffany P. Gustafson, Karen L. Wooley, Improving Paclitaxel Delivery: In Vitro and In Vivo Characterization of PEGylated Polyphosphoester-Based Nanocarriers, J. Am. Chem. Soc., DOI: 10.1021/ja512616s, Vol. 137, pp. 2056-2066, 2015
5-Mahmoud Elsabahy and Karen L. Wooley, Data Mining as a Guide for the Construction of Cross-Linked Nanoparticles with Low Immunotoxicity via Control of Polymer Chemistry and Supramolecular Assembly, Acc. Chem. Res., DOI: 10.1021/acs.accounts.5b00066, Vol. 48, pp. 1620-1630, 2015
البحث كاملا
6-Mahmoud Elsabahy, Gyu Seong Heo, Soon-Mi Lim, Guorong Sun and Karen L. Wooley, Polymeric Nanostructures for Imaging and Therapy, Chem. Rev., DOI: 10.1021/acs.chemrev.5b00135, Vol. 115, pp. 10967-11011, 2015
البحث كاملا
7-Jiong Zou, Fuwu Zhang, Shiyi Zhang, Stephanie F. Pollack, Mahmoud Elsabahy, Jingwei Fan, Karen L. Wooley, Poly(ethylene oxide)-block-Polyphosphoester-graft-Paclitaxel Conjugates with Acid-Labile Linkages as a pH-Sensitive and Functional Nanoscopic Platform for Paclitaxel Delivery, Adv. Healthcare Mater., DOI: 10.1002/adhm.201300235 , Vol. 3, No. 3, pp. 441-448, 2014
البحث كاملا
8-Young H. Lim, Gyu Seong Heo, Yohannes H. Rezenom, Stephanie Pollack, Jeffery E. Raymond, Mahmoud Elsabahy, Karen L. Wooley, Development of a Vinyl Ether-Functionalized Polyphosphoester as a Template for Multiple Postpolymerization Conjugation Chemistries and Study of Core Degradable Polymeric Nanoparticles, Macromolecules, dx.doi.org/10.1021/ma402480a, Vol. 47, pp. 4634-4644, 2014
9-Mahmoud Elsabahy, Shiyi Zhang, Fuwu Zhang, Zhou J. Deng, Young H. Lim, Hai Wang, Perouza Parsamian, Paula T. Hammond, Karen L. Wooley, Surface Charges and Shell Crosslinks Each Play Significant Roles in Mediating Degradation, Biofouling, Cytotoxicity and Immunotoxicity for Polyphosphoester-based Nanoparticles, Scientific Reports, DOI: 10.1038/srep03313, Vol. 3, 3313, pp. 1-10, 2013
10-Mahmoud Elsabahy, Ang Li, Fuwu Zhang, Deborah Sultan, Yongjian Liu, Karen L. Wooley, Differential Immunotoxicities of Poly(ethylene glycol)- vs. Poly(carboxybetaine)-Coated Nanoparticles, Journal of Controlled Release, http://dx.doi.org/10.1016/j.jconrel.2013.09.010, Vol. 172, pp. 641-652, 2013
11-Mahmoud Elsabahy, Sandani Samarajeewa, Jeffery E. Raymond, Corrie Clark, Karen L. Wooley, Shell-Crosslinked Knedel-like Nanoparticles Induce Lower Immunotoxicity than their Non-Crosslinked Analogs, Journal of Materials Chemistry B, DOI: 10.1039/c3tb20668h, Vol. 1, pp. 5241-5255, 2013
12-Mahmoud Elsabahy, Ritu Shrestha, Corrie Clark, Sara Taylor, Jeffrey Leonard, Karen L. Wooley, Multifunctional Hierarchically Assembled Nanostructures as Complex Stage-Wise Dual-Delivery Systems for Coincidental Yet Differential Trafficking of siRNA and Paclitaxel, Nano Letters, dx.doi.org/10.1021/nl4006645, Vol. 13, pp. 2172-2181, 2013
13-Shiyi Zhang, Jiong Zou, Mahmoud Elsabahy, Amolkumar Karwa, Ang Li, Dennis A. Moore, Richard B. Dorshow, Karen L. Wooley, Poly(ethylene oxide)-block-Polyphosphester-based Paclitaxel Conjugates as a Platform for Ultra-High Paclitaxel-Loaded Multifunctional Nanoparticles, Chemical Science, DOI: 10.1039/c3sc50252j, Vol. 4, pp. 2122-2126 , 2013
14-Fuwu Zhang, Mahmoud Elsabahy, Shiyi Zhang, Lily Yun Lin, Jiong Zou, Karen L. Wooley, Shell Crosslinked Knedel-like Nanoparticles for Delivery of Cisplatin: Effects of Crosslinking, Nanoscale, DOI: 10.1039/c3nr34320k, Vol. 5, pp. 3220-3225, 2013
15-Sandani Samarajeewa, Aida Ibricevic, Sean P. Gunsten, Ritu Shrestha, Mahmoud Elsabahy, Steven L. Brody, Karen L. Wooley, Degradable Cationic Shell Cross-Linked Knedel-like Nanoparticles: Synthesis, Degradation, Nucleic Acid Binding and In vitro Evaluation, Biomacromolecules, dx.doi.org/10.1021/bm3018774, Vol. 14, pp. 1018-1027, 2013
16-Mahmoud Elsabahy, Karen L. Wooley, Cytokines as Biomarkers of Nanoparticle Immunotoxicity, Chem. Soc. Rev., DOI: 10.1039/c3cs60064e, Vol. 42, pp. 5552-5576, 2013
17-Sandani Samarajeewa, Ritu Shrestha, Mahmoud Elsabahy, Amolkumar Karwa, Ang Li, Ryan P. Zentay, James G. Kostelc, Richard B. Dorshow, Karen L. Wooley, In vitro Efficacy of Paclitaxel-loaded Dual-responsive Shell Cross-Linked Polymer Nanoparticles Having Orthogonally Degradable Disulfide Cross-Linked Corona and Polyester Core Domains, Molecular Pharmaceutics, dx.doi.org/10.1021/mp3005897, Vol. 10, pp. 1092-1099, 2013
18-Mahmoud Elsabahy, Marianna Foldvari, Needle-free Gene Delivery Through the Skin: An Overview of Recent Strategies, Current Pharmaceutical Design, Vol. 19, No. 41, pp. 7301-7315, 2013
19-Ritu Shrestha , Mahmoud Elsabahy , Stephanie Florez-Malaver , Sandani Samarajeewa , Karen L. Wooley, Endosomal Escape and siRNA Delivery with Cationic Shell Crosslinked Knedel-Like Nanoparticles with Tunable Buffering Capacities, Biomaterials , http://dx.doi.org/10.1016/j.biomaterials.2012.07.054, Vol. 33, PP. 8557-8568 , 2012
20-Mahmoud Elsabahy, Karen L. Wooley, Strategies Toward Well-Defined Polymer Nanoparticles Inspired by Nature: Chemistry versus Versatility, Journal of Polymer Science, Part A: Polymer Chemistry, DOI: 10.1002/pola.25955, Vol.50, PP.1869–1880, 2012
21-Mahmoud Elsabahy and Karen L. Wooley, Design of Polymeric Nanoparticles for Biomedical Delivery Applications, Chem. Soc. Rev.,  DOI: 10.1039/c2cs15327k , Vol.41, PP. 2545–2561, 2012
22-Ritu Shrestha, Mahmoud Elsabahy, Hannah Luehmann, Sandani Samarajeewa, Stephanie Florez-Malaver, Nam S. Lee, Michael J. Welch, Yongjian Liu, Karen L. Wooley, Hierarchically Assembled Theranostic Nanostructures for siRNA Delivery and Imaging Applications, J. Am. Chem. Soc., dx.doi.org/10.1021/ja306616n, Vol. 134, pp. 17362-17365, 2012
23-Shiyi Zhang, Jiong Zou, Fuwu Zhang, Mahmoud Elsabahy, Simcha E. Felder, Jiahua Zhu, Darrin J. Pochan, Karen L. Wooley, Rapid and Versatile Construction of Diverse and Functional Nanostructures Derived from a Polyphosphoester-based Biomimetic Block Copolymer System, J. Am. Chem. Soc., dx.doi.org/10.1021/ja309037m, Vol. 134, pp. 18467-18474, 2012
24-Arnaud E. Felber, Bastien Castagner, Mahmoud Elsabahy, Glen F. Deleavey, Masad J. Damha, Jean-Christophe Leroux, siRNA Nanocarriers Based on Methacrylic Acid Copolymers, Journal of Controlled Release, doi:10.1016/j.jconrel.2010.12.012 , Elsevier, Vol. 152, pp. 159-167 , 2011
البحث كاملا
25-Mahmoud Elsabahy, Adil Nazarali, Marianna Foldvari, Non-Viral Nucleic Acid Delivery: Key Challenges and Future Directions, Current Drug Delivery, Vol. 8, No. 3, pp. 235-244, 2011
26-Hui Gao, Mahmoud Elsabahy, Elisabeth V. Giger, Jianbiao Ma, Robert E. Prud'homme, Jean-Christophe Leroux, Self Assembling Properties of Aminated Poly(glycerol methacrylate)s, Journal of Controlled Release, doi:10.1016/j.jconrel.2011.08.050, Vol. 152, pp. e142-e143, 2011
27-McDonald Donkuru, Ildiko Badea, Shawn Wettig, Ronald Verrall, Mahmoud Elsabahy, Marianna Foldvari, Advancing Nonviral Gene Delivery: Lipid- and Surfactant-Based Nanoparticle Design Strategies, Nanomedicine, vol. 5, No. 7, pp. 1103-1127, 2010
28-Hui Gao, Mahmoud Elsabahy, Elisabeth V. Giger, Dekun Li, Robert E. Prud’homme, Jean-Christophe Leroux, Aminated Linear and Star-Shape Poly(glycerol methacrylate)s: Synthesis and Self-Assembling Properties, Biomacromolecules, vol. 11, No. 4, pp. 889-895 , 2010
29-Mahmoud Elsabahy, Nada Wazen, Núria Bayó-Puxan, Glen Deleavey, Marc Servant, Masad J. Damha, Jean-Christophe Leroux, Delivery of Nucleic Acids Through the Controlled Disassembly of Multifunctional Nanocomplexes, Advanced Functional Materials, DOI: 10.1002/adfm.200901139, Vol. 19, pp. 3862 - 3867, 2009
30-Marie-Hélène Dufresne, Mahmoud Elsabahy, Jean-Christophe Leroux, Characterization of Polyion Complex Micelles Designed to Address the Challenges of Oligonucleotide Delivery, Pharmaceutical Research, DOI: 10.1007/s11095-008-9591-6, vol. 25, No. 9, pp. 2083-2093, 2008
31-Mahmoud Elsabahy, Mingzhen Zhang, Shao-Ming Gan, Karen C. Waldron, Jean-Christophe Leroux, Synthesis and Enzymatic Stability of PEGylated Oligonucleotide Duplexes and their Self-Assemblies with Polyamidoamine Dendrimers, Soft Matter, DOI: 10.1039/b714221h, vol. 4, pp. 294-302, 2008
32-Mahmoud Elsabahy, Marie-Ève Perron, Nicolas Bertrand, Ga-er Yu, Jean-Christophe Leroux, Solubilization of Docetaxel in Poly(ethylene oxide)-block-poly(butylene/styrene oxide) Micelles, Biomacromolecules, vol. 8, No. 7, pp. 2250-2257, 2007
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