إجمالى الأبحاث : 180 - من 1 إلى 10

1 - Authors: Tarek Aboul-Fadl, Soliman A. Al-Hamad, Ehab A. Fouad
Title: "Pharmacokinetic studies of naproxen amides of some amino acid esters with promising colorectal cancer chemopreventive activity"
Source: Bioorganic Chemistry , In Press, 2018, https://doi.org/10.1016/j.bioorg.2017.12.006 0045-2068/© 2017.

2 - Authors: Tilal Elsaman, Omar A. Al-Deeb, Tarek Aboul-Fadl.
Title: "Synthesis, Characterization and Antiproliferative Activity of Certain Meclofenamic Acid Amides"
Source: Asian Journal of Chemistry, 29(2), 291-295 , 2, 2017, http://www.asianjournalofchemistry.co.in/user/journal/viewarticle.aspx?ArticleID=29_2_12

3 - Authors: Hajjaj H. M. Abdu-Allah, Bahaa G. M. Youssif, Mostafa H. Abdelrahman, Mohammed K. Abdel-Hamid, Rudraraju S. Reshma, Perumal Yogeeswari, Tarek Aboul-Fadl, Dharmarajan Sriram
Title: "Synthesis and Anti-Mycobacterial Activity of 4-(4-phenyl-1H-1,2,3-triazol-1-yl)salicylhydrazones: Revitalizing an Old Drug"
Source: Archives of Pharmacal Research , Vol, 40, No. 2, pp. 168-179, 2, 2017, http://link.springer.com/article/10.1007/s12272-016-0882-x?wt_mc=Internal.Event.1.SEM.ArticleAuthorAssignedToIssue>
Keywords: Antitubercular, p-Aminosalicylic, Dormant TB, Triazole, Isatin, Hydazide and modeling

4 - Authors: Tilal Elsaman, Omar A.A. Aldeeb, Tarek Aboul-Fadl, Elnazeer I. Hamedelneil
Title: "Synthesis, characterization and pharmacological evaluation of certain enzymatically cleavable NSAIDs amide prodrugs"
Source: Bioorganic Chemistry , 70(2), 144-152, 2, 2017, http://dx.doi.org/10.1016/j.bioorg.2016.12.005
Keywords: NSAIDs Prodrugs Amino acid ester Ulcerogenicity

5 - Authors: Luke R Odell, Mohammed K Abdel-Hamid, Timothy A Hill, Ngoc Chau, Kelly A Young, Fiona M Deane, Jennette A Sakoff, Sofia Andersson, James A Daniel, Phillip J Robinson, Adam McCluskey
Title: "Pyrimidine-based inhibitors of Dynamin I GTPase activity: Competitive inhibition at the pleckstrin homology domain"
Source: Journal of Medicinal Chemistry , 60, 349–361, 2017

6 - Authors: Azza H. Rageh, Noha N. Atia, Hamdy M. Abdel-Rahman
Title: "Lipophilicity Estimation of Statins as a Decisive Physicochemical Parameter for Their Hepato-Selectivity Using Reversed-Phase Thin Layer Chromatography"
Source: Journal of Pharmaceutical and Biomedical Analysis , Vol. 142, pp. 7-14, 4, 2017, http://dx.doi.org/10.1016/j.jpba.2017.04.037
Keywords: Reversed-phase thin layer chromatography, Relative lipophilicity, Statins, Hepato-selectivity, Quantitative structure-retention, relationship (QSRR), Quantitative structure-property, relationship (QSPR)

7 - Authors: Tilal Elsaman, Omar A. A. Aldeeb, Tarek Aboul-Fadl and Abdullah Al-Dhfyan
Title: "Synthesis and antiproliferative activity of some novel amides of flufenamic acid and diclofenac"
Source: Der Pharma Chemica , 8(2), 434-443 , 2, 2016, http://derpharmachemica.com/vol8-iss2/DPC-2016-8-2-434-443.pdf

8 - Authors: Carolynn C. Arpin, Stephen Mac, Yanlin Jiang, Huiwen Cheng, Michelle Grimard, Brent D. G. Page, Malgorzata M. Kamocka, Sina Haftchenary, Han Su, Daniel Ball, David A. Rosa, Ping-Shan Lai, Rodolfo F. Gómez-Biagi, Ahmed M. Ali1,5, Rahul Rana, Helmut Hanenberg, Kagan Kerman, Kyle C McElyea, George E. Sandusky, Patrick T. Gunning, Melissa L. Fishel
Title: "Applying Small Molecule Signal Transducer and Activator of Trancription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics "
Source: Molecular Cancer Therapeutics, 2, 2016, DOI: 10.1158/1535-7163.MCT-15-0003
Keywords: STAT3, three-dimensional culture, efficacy, transcription factor

9 - Authors: Ahmed M. Ali,Rodolfo F. Gmez-Biagi, David A. Rosa, Ping-Shan Lai, William L. Heaton, Ji Sung Park, Anna M. Eiring, Nadeem A. Vellore,Elvin D. de Araujo, Dan P. Ball, Andrew E. Shouksmith, Ami B. Patel, Michael W. Deininger, Thomas O’Hare, and Patrick T. Gunning
Title: "Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities"
Source: ChemMedChem, DOI: 10.1002/cmdc.201600021 , Vol. 11, No. 8, pp. 850-861, 3, 2016, http://dx.doi.org/10.1002/cmdc.201600021
Keywords: chronic myeloid leukemia· covalent modification· imatinib resistance· protein–protein interactions· STAT3

10 - Authors: Trieu Trinh, Eileen A McLaughlin, Mohammed K. Abdel-Hamid, Christopher Gordon, Victoria Aye, Peter Cossar, Jennette Sakoff, Adam McCluskey
Title: "Quinolone-1-(2H)-ones as Hedgehog Signalling Pathway Inhibitors"
Source: Organic & Biomolecular Chemistry, 2016

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