إجمالى الأبحاث : 76 - من 1 إلى 10

1 - Authors: El-Nagar MKS, Abdu-Allah HHM, Salem OIA, Kafafy AN, Farghaly HSM.
Title: "Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study."
Source: Bioorg Chem, 6;78, 80-93, 3, 2018
Keywords: 5-Aminosalicylamides; Anti-inflammatory agents; COX-2 & 5-LOX inhibitors; Molecular docking

2 - Authors: Mohamed K.S. El-Nagar, Hajjaj H.M. Abdu-Allah, Ola I.A. Salem, Abdel-Hamid N. Kafafy and Hanan S.M. Farghaly
Title: "Novel N-Substituted 5-aminosalicylamides as Dual Inhibitors of Cyclooxygenase and 5-Lipoxygenase Enzymes: Synthesis, Biological Evaluation and Docking Study"
Source: Bioorganic Chemistry, Vol. 78, pp. 80–93, 2018, https://doi.org/10.1016/j.bioorg.2018.02.023
Keywords: 5-Aminosalicylamides, Anti-inflammatory agents, COX-2 & 5-LOX inhibitors, Molecular docking

3 - Authors: Bahaa G.M. Youssif, Mostafa H. Abdelrahman, Ahmed H. Abdelazeem, Mohamed A. Abdelgawad, Hussein M. Ibrahim, Ola I.A. Salem, Mamdouh F.A. Mohamed, Laurent Treambleau, Syed Nasir Abbas Bukhari
Title: "Design, Synthesis, Mechanistic and Histopathological Studies of Small-Molecules of Novel Indole-2-Carboxamides and Pyrazino[1,2-a]indol-1(2H)-ones as Potential Anticancer Agents Effecting the Reactive Oxygen Species Production"
Source: European Journal of Medicinal Chemistry, Vol. 146 , pp. 260-273, 2018, https://doi.org/10.1016/j.ejmech.2018.01.042
Keywords: Indole-2-carboxamides, Pyrazino[1,2-a]indole, EGFR, BRAF, Docking, Anti-cancer, Anti-oxidant

4 - Authors: Hajjaj H. M. Abdu-Allah, Bahaa G. M. Youssif, Mostafa H. Abdelrahman, Mohammed K. Abdel-Hamid, Rudraraju S. Reshma, Perumal Yogeeswari, Tarek Aboul-Fadl, Dharmarajan Sriram
Title: "Synthesis and Anti-Mycobacterial Activity of 4-(4-phenyl-1H-1,2,3-triazol-1-yl)salicylhydrazones: Revitalizing an Old Drug"
Source: Archives of Pharmacal Research , Vol, 40, No. 2, pp. 168-179, 2, 2017, http://link.springer.com/article/10.1007/s12272-016-0882-x?wt_mc=Internal.Event.1.SEM.ArticleAuthorAssignedToIssue>
Keywords: Antitubercular, p-Aminosalicylic, Dormant TB, Triazole, Isatin, Hydazide and modeling

5 - Authors: Hajjaj H.M. Abdu-Allah, Tzu Ting Chang, Wen-Shan Li
Title: "Synthesis of B- and C-Ring-Modified Lithocholic Acid Analogues as Potential Sialyltransferase Inhibitors"
Source: Steroids , Vol. 112, pp. 54-61, 2016, http://dx.doi.org/10.1016/j.steroids.2016.04.013
Keywords: Lithocholic acid, Homolactone, Homolactam, Oxidation, Rearrangement, Sialyltransferase inhibitors

6 - Authors: Bahaa G.M. Youssif, Yaseen A.M. Mohamed, Mohammed T.A. Salim, Fuyuhiko Inagaki, Chisato Mukai, Hajjaj H.M. Abdu-Allah
Title: "Synthesis of Some Benzimidazole Derivatives Endowed with 1,2,3-Triazole as Potential Inhibitors of Hepatitis C Virus"
Source: Acta Pharm., DOI: 10.1515/acph-2016-0014 , Vol. 66, pp. 219-231, 2016
Keywords: Benzimidazole, triazole, anilide, antiviral, HCV, HBV

7 - Authors: Hajjaj H.M. Abdu-Allah, Shih-Ting Huang, Tzu Ting Chang, Chia-Ling Chen, Han-Chung Wu, Wen-Shan Li
Title: "Nature-Inspired Design of Tetraindoles: Optimization of the Core Structure and Evaluation of Structure–Activity Relationship"
Source: Bioorganic & Medicinal Chemistry Letters , Vol. 26, pp. 4497-4503, 2016, http://dx.doi.org/10.1016/j.bmcl.2016.07.069
Keywords: Tetraindoles, Anticancer, Core, Apoptosis, Planarity

8 - Authors: Hajjaj H.M. Abdu-Allah, Samia G. Abdel-Moty, Raafat El-Awady, Abdel-Nasser A. El-Shorbagi
Title: "Design and Synthesis of Novel 5-Aminosalicylate (5-ASA)–4-Thiazolinone Hybrid Derivatives with Promising Antiproliferative Activity"
Source: Bioorganic & Medicinal Chemistry Letters , Vol. 26, pp. 1647-1650, 2016, http://dx.doi.org/10.1016/j.bmcl.2016.02.073
Keywords: 5-Aminosalicylic, 4-Thiazolinone, 4-Thiazolidinone, Stereochemistry, Hybrid, Antiproliferative

9 - Authors: Hajjaj H. M. Abudu-AllAh, Hideharu Ishida, Makoto Kiso
Title: "Design and Synthesis of Ligands and Antagonists of Siglecs as Immune Response Modifiers"
Source: Wiley: Glycochemical Synthesis: Strategies and Applications , First ed. , pp. 483-507, 2016, http://eu.wiley.com/WileyCDA/WileyTitle/productCd-1118299841.html

10 - Authors: Hajjaj H. M. Abdu-Allah, Talaat I. El-Emary
Title: "Synthesis and Preliminary Biological Screening of 6-Aminopyrazolo[3,4-b]pyridine Derivatives"
Source: Der Pharma Chemica , Vol. 8, No. 16, pp. 9-16, 2016
Keywords: 6-Aminopyrazolo[3,4-b]pyridines, Nucleophilic substitution, cytotoxicity, COX inhibition, antimicrobial

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