Noninvasive ventilation in COVID-19 patients aged ≥ 70 years-a prospective multicentre cohort study

Faculty of Medicine

Assiut University

Noninvasive ventilation in COVID-19 patients aged ≥ 70 years-a prospective multicentre cohort study

Research Authors
Kamil Polok, Jakub Fronczek, Antonio Artigas, Hans Flaatten, Bertrand Guidet, Dylan W. De Lange, Jesper Fjølner, Susannah Leaver, Michael Beil, Sigal Sviri, Raphael Romano Bruno, Bernhard Wernly, Bernardo Bollen Pinto, on behalf of COVIP Study group
Research Date
Research Department
Department of Chest Diseases
Research Journal
Critical Care
Research Member
Aliae Abd Rabou Mohamed Hussein
Research Publisher
Springer Link
Research Vol
26
Research Website
https://doi.org/10.1186/s13054-022-04082-1
Research Year
2022
Research Abstract

Background

Noninvasive ventilation (NIV) is a promising alternative to invasive mechanical ventilation (IMV) with a particular importance amidst the shortage of intensive care unit (ICU) beds during the COVID-19 pandemic. We aimed to evaluate the use of NIV in Europe and factors associated with outcomes of patients treated with NIV.

Methods

This is a substudy of COVIP study—an international prospective observational study enrolling patients aged ≥ 70 years with confirmed COVID-19 treated in ICU. We enrolled patients in 156 ICUs across 15 European countries between March 2020 and April 2021.The primary endpoint was 30-day mortality.

Results

Cohort included 3074 patients, most of whom were male (2197/3074, 71.4%) at the mean age of 75.7 years (SD 4.6). NIV frequency was 25.7% and varied from 1.1 to 62.0% between participating countries. Primary NIV failure, defined as need for endotracheal …