Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data set

Faculty of Medicine

Assiut University

Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data set

Research Authors
Andrew Conway Morris, Katharina Kohler, Thomas De Corte, Ari Ercole, Harm-Jan De Grooth, Paul W. G. Elbers, Pedro Povoa, Rui Morais, Despoina Koulenti, Sameer Jog, Nathan Nielsen, Alasdair Jubb, Maurizio Cecconi for the ESICM UNITE COVID investigators
Research Date
Research Department
Department of Chest Diseases
Research Journal
Critical Care
Research Member
Aliae Abd Rabou Mohamed Hussein
Research Publisher
Springer
Research Vol
26
Research Website
https://doi.org/10.1186/s13054-022-04108-8
Research Year
2022
Research Abstract

Background

The COVID-19 pandemic presented major challenges for critical care facilities worldwide. Infections which develop alongside or subsequent to viral pneumonitis are a challenge under sporadic and pandemic conditions; however, data have suggested that patterns of these differ between COVID-19 and other viral pneumonitides. This secondary analysis aimed to explore patterns of co-infection and intensive care unit-acquired infections (ICU-AI) and the relationship to use of corticosteroids in a large, international cohort of critically ill COVID-19 patients.

Methods

This is a multicenter, international, observational study, including adult patients with PCR-confirmed COVID-19 diagnosis admitted to ICUs at the peak of wave one of COVID-19 (February 15th to May 15th, 2020). Data collected included investigator-assessed co-infection at ICU admission, infection acquired in ICU, infection with multi-drug …