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Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave: the global UNITE-COVID study

Research Authors
Massimiliano Greco, Thomas De Corte, Ari Ercole, Massimo Antonelli, Elie Azoulay, Giuseppe Citerio, Andy Conway Morris, Gennaro De Pascale, Frantisek Duska, Paul Elbers, the ESICM UNITE-COVID investigators
Research Journal
Intensive Care Med
Research Publisher
Springer
Research Vol
48
Research Website
https://doi.org/10.1007/s00134-022-06705-1
Research Year
2022
Research Abstract

Purpose

To accommodate the unprecedented number of critically ill patients with pneumonia caused by coronavirus disease 2019 (COVID-19) expansion of the capacity of intensive care unit (ICU) to clinical areas not previously used for critical care was necessary. We describe the global burden of COVID-19 admissions and the clinical and organizational characteristics associated with outcomes in critically ill COVID-19 patients.

Methods

Multicenter, international, point prevalence study, including adult patients with SARS-CoV-2 infection confirmed by polymerase chain reaction (PCR) and a diagnosis of COVID-19 admitted to ICU between February 15th and May 15th, 2020.

Results

4994 patients from 280 ICUs in 46 countries were included. Included ICUs increased their total capacity from 4931 to 7630 beds, deploying personnel from other areas. Overall, 1986 (39.8%) patients were admitted to surge capacity beds