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Clinical course, viral etiology, and the diagnostic workup for patients with suspected myocarditis: a single-center prospective study

Research Authors
Shimaa S Khidr, Mohamed Ahmed El-Mokhtar, Shery Refaat Asaad, Helal F Hetta, Mona Hussein Abdel-Rahim, Amr Ahmed Aly Youssef, Ayman KM Hassan
Research Date
Research Department
Research Journal
BMC Cardiovascular Disorders
Research Year
2022
Research Abstract

Myocarditis is a highly heterogeneous disorder with a challenging diagnostic work-up. We aimed to focus on the possible diagnostic workup for this condition in settings where endomyocardial biopsy as a gold standard is not always feasible, detect the etiologic cardiotropic viruses in our locality, and follow the clinical course in patients admitted with clinically suspected myocarditis.

Methods

This is a prospective observational study. We recruited patients with clinically suspected myocarditis presenting at a university hospital from October 1st, 2020 until March 31st, 2021. All Patients had a diagnostic coronary angiography and were included only if they had a non-obstructive coronary artery disease. All patients also had cardiac magnetic resonance imaging (CMR) with contrast. Sera were obtained from all suspected patients for detection of antibodies against viruses using enzyme-linked immunosorbent