Environmental stressors, such as heavy metal pollution, can have devastating effects on biological organisms, leading to conditions like liver toxicity. This study explored the therapeutic potential of a novel iron-based metal-organic framework (Fe-MOF) in mitigating cobalt chloride-induced liver toxicity in rats.

Utilizing a solvothermal synthesis method, CWP/MOF was created and characterized using X-ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy. Adult male rats were divided into four groups, each consisting of six rats. The groups were treated as follows: Group 1 (Control): Received 0.5 ml/day of distilled water only. Group 2 (CoCl₂): Treated with cobalt chloride (100 mg/kg/day) dissolved in distilled water. Group 3 (CoCl₂ + Fe-MOFs): Treated with cobalt chloride (100 mg/kg/day) and Fe-MOFs dissolved in distilled water. Group 4 (CoCl₂ …