Prof. Khalid Ibrahim Abdel-Rahman El-Sayeh

Professor, Department of Pediatrics , Faculty of Medicine, ِِAssiut University

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Educational Qualifications:
  • Ph. D., 2005
  • M. Sc., 1998
  • B. Sc., 1993
  • Professor, Department of Pediatrics , Faculty of Medicine, ِِAssiut University, 2015
  • Associate Professor, Department of Pediatrics , Faculty of Medicine, ِِAssiut University, 2010
  • Lecturer, Department of Pediatrics , Faculty of Medicine, Assiut University, 2005
  • Assistant Lecturer, Department of Pediatrics , Faculty of Medicine, Assiut University, 1999
  • Demonstrator, Department of Pediatrics , Faculty of Medicine, Assiut University, 1999

Research fields:
hematology , immunology , malnutrition


1 - Zahran AM1, Nafady A2,3, Saad K4, Hetta HF5, Abdallah AM4, Abdel-Aziz SM4, Embaby MM4, Abo Elgheet AM4, Darwish SF6, Abo-Elela MGM4, Elhoufey A7, Elsayh KI4., Effect of Hydroxyurea Treatment on the Inflammatory Markers Among Children With Sickle Cell Disease., Clin Appl Thromb Hemost. , Clin Appl Thromb Hemost. 2020 Jan-Dec;26:1076029619895111. doi: 10.1177/1076029619895111., Clin Appl Thromb Hemost. 2020 Jan-Dec;26:10760296198951, January, 2020
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2 - Asmaa M Zahran, Omnia El-Badawy, Khalid I Elsayh, Wael MY Mohamed, Khalid F Riad, Mona H Abdel-Rahim, Amal Rayan, Upregulation of CD146 in Pediatric B-Cell Acute Lymphocytic Leukemia and Its Implications on Treatment Outcomes, Journal of Immunology Research, February, 2020
3 - Asmaa M. Zahran, MD1, Khalid I. Elsayh, MD2, Khaled Saad, MD2 , Mostafa M. Embaby, MD2, Mervat A. M. Youssef, MD2, Yasser F. Abdel-Raheem, MD2, Shaban M. Sror, MD2, Shereen M. Galal, MD2, Helal F. Hetta, MD3 , Mohamed Diab Aboul-Khair, MD4, Mohamd A. Alblihed, PhD5, and Amira Elhoufey, PhD6,7, Circulating Microparticles in Children With Sickle Cell Anemia in a Tertiary Center in Upper Egypt, Clinical and Applied Thrombosis/Hemostasis, January, 2019
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4 - Asmaa M. Zahran1 · Mona H. Abdel‑Rahim2 · Khalid I. Elsayh3 · Manal M. Hassanien4 · Safaa A. Mahran4 · Helal F. Hetta2,5, Natural Killer and Natural Killer T Cells in Juvenile Systemic Lupus Erythematosus: Relation to Disease Activity and Progression, Archivum Immunologiae et Therapiae Experimentalis, springer, April, 2019
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5 - Asmaa M. Zahran Alameldin M. Abdallah Khaled SaadEmail author Naglaa S. Osman Mervat A. M. Youssef Yasser Farouk Abdel-Raheem Khalid I. Elsayh Amir M. Abo Elgheet Sanaa F. Darwish Mohamd A. Alblihed Amira Elhoufey, Peripheral Blood B and T Cell Profiles in Children with Active Juvenile Idiopathic Arthritis., Arch Immunol Ther Exp (Warsz). 2019 Sep 18. doi: 10.1007/s00005-019-00560-7. [Epub ahead of print], springer, Archivum Immunologiae et Therapiae Experimentalis.ISSN: 0004-069X (Print) 1661-4917 (Online) Volume 67 , pp 1–6, September, 2019
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6 - Amr M Kotb Salah el-din Amry Khaled Elsayeh Ahmed Ghoneim, Physical Fitness Study in Children with Previous Surgery for Congenital Heart Disease, International Journal of Cardiovascular Research, September, 2019
7 - Asmaa M. Zahran · Khaled Saad · Yasser F. Abdel‑Raheem · Khalid I. Elsayh · Amira A. El‑Houfey· Mohamed Diab Aboul‑Khair · Mohamd A. Alblihed, Characterization of regulatory T cells in preterm and term Infants. , Archivum Immunologiae et Therapiae Experimentalis, Springer, 67, 49-54, February, 2019
8 - Zahran A, El-Badawy O, Mohamad I, Tamer D, Abdel-Aziz S, Elsayh K, Platelet activation and platelet-leukocyte aggregates in type 1 diabetes mellitus , Clinical and Applied Thrombosis/Hemostasis, 1076029618805861, 2018
9 - Khaled Saad1 · Asmaa M. Zahran2· Khalid I. Elsayh1· Abobakr Abdelmoghny3 · Mohamed Diab Aboul‑Khair4, Variation of Regulatory T Lymphocytes in the Peripheral Blood of Children with Allergic Rhinitis, Archivum Immunologiae et Therapiae Experimentalis , 8, 2018
10 - Mervat AM Youssef, Eman Salah Eldeen, Khalid I Elsayh, Samaher F Taha, Mohamed Gamil M Abo-Elela , High dose dexamethasone as an alternative rescue therapy for active bleeding in children with chronic ITP: clinical and immunological effects, Platelets, October, 2018
11 - Asmaa M. Zahran1· Khaled Saad2 · Yasser F. Abdel‑Raheem2 · Khalid I. Elsayh2 · Amira A. El‑Houfey3,4 ·Mohamed Diab Aboul‑Khair5· Mohamd A. Alblihed6, Characterization of Regulatory T Cells in Preterm and Term Infants, Archivum Immunologiae et Therapiae Experimentalis , October, 2018
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12 - Asmaa M. Zahran, MD1, Khaled Saad, MD2 , Khalid I. Elsayh, MD2, Abobakr Abdelmoghny, MD3, Mohamed Diab Aboul-Khair, MD4, Ali Sobhy, MD5, Yasser F Abdel-Raheem, MD2, Osama M. El-Asheer, MD2, Amira A. El-Houfey, PhD6,7, Mohamd A. Alblihed, MD8, and Ibrahim Al-Neami, MSC9, Myeloid-Derived Suppressor Cells and Costimulatory Molecules in Children With Allergic Rhinitis, Annals of Otology, Rhinology & Laryngology, 2018
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13 - Sayed M, El Sayah K, Ahmed E, Auditing nursing care for children receiving blood transfusion at Assiut university Children Hospital, Assiut Scientific Nursing Journal , 2018
14 - MD2 Asmaa M. Zahran, MD1 , Ismail L. Mohamed, MD2 , Osama M. El Asheer, MD2 , Deiaaeldin M. Tamer, MD2 , Mohamed G. M. Abo-ELela, MD2 , Mona H. Abdel-Rahim, MD3 , Omnia H. B. El-Badawy, MD3 , and Khalid I. Elsayh, Circulating Endothelial Cells, Circulating Endothelial Progenitor Cells, and Circulating Microparticles in Type 1 Diabetes Mellitus, Journal Clinical and Applied Thrombosis/Hemostasis , Volume 25., 1-7, December, 2018
15 - Khaled Saad, Asmaa M. Zahran, Khalid I. Elsayh, Abobakr Abdelmoghny & Mohamed Diab Aboul-Khair, Variation of Regulatory T Lymphocytes in the Peripheral Blood of Children with Allergic Rhinitis. , Archivum Immunologiae et Therapiae Experimentalis , Springer, 66(4), 307-313, June, 2018
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16 - Asmaa M. Zahran • Azza A. Eltayeb • Khalid I. Elsayh • Khaled Saad • Faisal-Alkhateeb Ahmad • Ahmad I. M. Ibrahim, Activated and Memory T Lymphocytes in Children with Gaucher Disease, Archivum Immunologiae et Therapiae Experimentalis , springer, 65(3), 263-269, June, 2017
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17 - Asmaa M. Zahran, MD1, Mervat A. M. Youssef, MD2, Khalid I. Elsayh, MD2, Mustafa M. Embaby, MD2, and Ahmad I. M. Ibrahim, MD2, Clinical Significance of T-Cell Immunoglobulin Mucin 3 Expression on Peripheral Blood Mononuclear Cells in Pediatric Acute Immune Thrombocytopenia, Clinical and Applied Thrombosis/Hemostasis, 2017
18 - Khaled Saad, Asmaa M. Zahran, Khalid I. Elsayh, Ahmed A. Abdel-Rahman, Abdulrahman A. Al-Atram, Almontaser Hussein, et al., Frequency of Dendritic Cells and Their Expression of Costimulatory Molecules in Children with Autism Spectrum Disorders, J Autism Dev Disord, 2017
19 - Asmaa M. Zahran1, MD, Azza A. Eltayeb2, MD, Khalid I. Elsayh2, MD, Khaled Saad2*, MD, CHANGES IN LYMPHOCYTE SUBPOPULATIONS AND CD3* HLA-DR+ IN CHILDREN WITH GAUCHER DISEASE, مؤتمر طب الاطفال العالمى والمنعقد فى فانكوفر بكندا, 8, 2016
20 - Asmaa M. Zahran a, Khalid I. Elsayhb, Khaled Saad b,⁎, Mostafa Embaby b, Ahmed M. Ali b, Regulatory B cells (CD19+CD38hiCD24hi) in alloimmunized and non-alloimmunized children with β-thalassemia major, Blood Cells, Molecules and Diseases , pp. 91–96, 2016
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21 - Asmaa M. Zahran1 · Khaled Saad2 · Khalid I. Elsayh2 · Mohamd A. Alblihed3, Characterization of circulating CD4+ CD8+ double positive and CD4− CD8− double negative T‑lymphocyte in children with β‑thalassemia major, Int J Hematol , 2016
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22 - Mohammed H. Hassan, Ayat A. Sayed, Ahmed El-Abd Ahmed, Tahia H. Saleem, Khalid I. Elsayh and Norhan B. B. Mohammed, Effect of Enzyme Replacement Therapy on Disease Burden Biomarkers in Gaucher's Disease, International Journal of Biochemistry Research , Vol.15, No.2, PP.1-6, 2016
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23 - Sohaila, F. H., Hassanein R, Agban MN, Elsayh KI , Effect of Thyme Extract on Some Enterobacteriaceae Isolated From Some Meat Products in Assuit City. Int Clin Pathol, Int Clin Pathol, 3 (1): 00069.DOI: 10.15.406/icpjl.2016.03.00069., 3 (1): 00069.DOI: 10.15.406/icpjl.03.00069., 2016
24 - Asmaa M. Zahran, Khalid I. Elsayh, Khaled Saad, Esraa M.A. Eloseily, Naglaa S. Osman, Mohamd A. Alblihed, Gamal Badr, Mohamed H. Mahmoud, Effects of royal jelly supplementation on regulatory T cells in children with SLE., Food and Nutrition Research, CO-publishing center, 60:32963., 1-10, November, 2016
25 - Asmaa Mohamed Zahran MD. Khalid Ibrahim El Sayh, MD Ismail Lotfy , MD. Gamal Mohamed Hassen, MD. And Madleen Adel A. Abdou, MD, Circulating Endothelial Cells and Endothelial Progenitor Cells in PediarticSepsis.Pediatric Emergency Care., .Pediatric Emergency Care, Asmaa Mohamed Zahran, 32 (3), 5, March, 2016
26 - Zahran AM, Elsayh KI, Sahar E.M. El-Deek, Mona A.H. El-Baz, . Oxidative Stress, Trace Elements, and Circulating Microparticles in Patients With Gaucher Disease Before and After Enzyme Replacement Therapy, Clin Appl Thromb Hemost, 2015
27 - Khalid I. Elsayh • Wafaa S. Mohammed • Asmaa M. Zahran • Khaled Saad, Leukocytes apoptosis and adipocytokines in children with beta thalassemia major, Clin Exp Med, June, 2015
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28 - Hassanein, R., Ali, Sohaila, F. H., Elsayh, K. I., Hussein, A. , A cohort study on shiga toxin producing E. coli O157:H7 isolated from some meat products in Assuit Governorate as a cause of bloody diarrhea in children. , Assiut Vet. Med. J. , Assiut Vet. Med. J., 61 (147). , 2015
29 - Khaled Saad, Khalid I. Elsayh, Asmaa M. Zahran, Karema M. Sobhy, Lymphocyte populations and apoptosis of peripheral blood B and T lymphocytes in children with end stage renal disease, Ren Fail, Informa Healthcare USA,, February, 2014
30 - Ismail Lotfy Mohamad, Khalid I. Elsayh,, Hanaa A. Mohammad, Khaled Saad, Asmaa M. Zahran, Alameldin M. Abdallah, M. S. K. Tawfeek, Eman M. Monazea. , Clinical characteristics and outcome of children stung by scorpion. Eur J Pediatr, Eur J Pediatr, 2014
31 - Asmaa M Zahran,Sanaa Shaker Aly,Khalid I Elsayh Ahlam Bahdawy, Yasser Gamal, Glucocorticoid receptors expression and histopathological types in children with nephrotic syndrome. , Ren Fail., 2014
32 - Samir A. Ammar , Khalid I. Elsayh , Asmaa M. Zahran , Mostafa Embaby, Splenectomy for patients with β-thalassemia major: long-term outcomes, The Egyptian Journal of Surgery, 2014
33 - Khalid . Elsayh , Asmaa M. Zahran , Ismail Lotfy Mohamad, Sanaa Shaker Aly, Dendritic cells in childhood sepsis, Journal of Critical Care , Vol.28, PP.881.e7–881.e13, 2013
34 - Khalid I Elsayh, Douaa M Sayed, Asmaa M Zahran, Khaled Saad, and Gamal Badr, Effects of pneumonia and malnutrition on the frequency of micronuclei in peripheral blood of pediatric patients, Int J Clin Exp Med. , Vol.6, No.10, PP.942–950., 2013
35 - Asmaa Mohamad Zahran & Khalid Ibrahim Elsayh & Hekma Saad Farghaly, Dendritic cells frequency and phenotype in Egyptian type 1 diabetic patients , Int J Diabetes Dev Ctries, 2013
36 - Khalid I. Elsayh, Asmaa M. Zahran , Taghrid . El-Abaseri , Amany O. Mohamed , Tarek H. El-Metwally , Hypoxia Biomarkers, Oxidative Stress, and Circulating Microparticles in Pediatric Patients with Thalassemia in Upper Egypt., Clin Appl Thromb Hemost. , January, 2013
37 - خالد ابراهيم السايح¹ , أسماء محمد زهران² , إسماعيل لطفى محمد¹ , سناء شاكر على³, Dendritic cells in childhood sepsis الخلايا الشجيرية فى تسمم الدم فى مرحلة الطفولة , Journal of Critical Care (2013) 28, 881.e7–881.e13 Impact Factor: 2.191 مجلة الرعاية الحرجة العدد 28 صفحة 881(e7-e13)- لسنة 2013 , 28, 881.e7–881.e13, 881.e7–881.e13, 2013
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38 - *Amel A. Mohamed,** Khalid I.El Sayh, *Safaa A.M. Kotb, *Neama M .El Magrabi , Mothers' Knowledge and Attitude Regarding Acute Diarrheal Disease at Outpatient Clinic ,Assiut University Children's Hospital, Assiut scientific nursing journal, Assiut scientific nursing journal, vol(1).No(2), Pp.108-115,, December, 2013
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39 - Asmaa Mohamed Zahran1, Khalid Ibrahem Elsayh2, Kotb Abbass Metwalley2, Regulatory T cells in children with recently diagnosed type 1 diabetes, Indian J Endocrinol Metab. , Vol. 16 - No.6, pp. 952 - 957, 2012
40 - Zahran AM, Elsayh KI., CD4+CD25+High FoxP3+ Regulatory T Cells, B Lymphocytes, and T Lymphocytes in Patients With Acute ITP in Assiut Children Hospital., Clin Appl Thromb Hemost. , 2012
41 - Dalia G. Mahran*, Mostafa Hussein**, Khaled E. El-Saeih***, Eman Nasr Eldin****, Amal M. Abdel-Aal****, Maternal anemia and its consequences on cord blood hematologic parameters, El-Minia Medical Bulletin, vol. 23 (2), June 2012:45-56., 23 (2), 45-56, June, 2012
42 - Asmaa Mohamed Zahran, Khalid Ibrahem Elsayh1, Kotb Abbass Metwalley1, Regulatory T cells in children with recently diagnosed type 1 diabetes, Indian Journal of Endocrinology and Metabolism, Vol. 16- No. 6, December, 2012
43 - Hassanein Raafat, Sohaila Fathi Hassan Ali, Ashraf Mohamed Abd El-Malek, Moemen A Mohamed and Khalid Ibrahim Elsayh, Detection and identification of Salmonella species in minced beef and chicken meats by using Multiplex PCR in Assiut city, Veterinary World, 2011
44 - Badr G, Sayed D, Alhazza IM, Elsayh K, Ahmed EA, Alwasel SH , T lymphocytes from malnourished infants are short-lived and dysfunctional cells , Immunobiology. , 2011
45 - Raafat Hassanein , Sohaila Fathi Hassan Ali , Ashraf Mohamed Abd El-Malek , 3 4 Moemen, A. Mohamed * and Khalid Ibrahim Elsayh , Detection and identification of Salmonella species in minced beef and chicken meats by using Multiplex PCR in Assiut city , Veterinary world , 4(1), 5-11, 2011
46 - SOHAILA FATHI HASSAN ALI; R. HASSANEIN , A. MOHAMED ABD EL-MALEK and K. IBRAHIM ELSAYH , INCIDENCE AND CHARACTERIZATION OF E. COLI O157:H7 ISOLATED FROM MINCED BEEF, CHICKEN MEATS AND HUMAN STOOLS IN ASSIUT CITY , Assiut Vet. Med. J. , Vol. 56 - No. 125 , Escherichia coli- E. coli O157:H7, minced beef, chicken fillet, chicken legs, children stools., April, 2010
47 - Khalid I. Elsayh, Douaa Sayed, Gamal Badr, Fas-induced apoptosis in malnourished infants [, Pediatric Allergy and Immunology , April, 2010
48 - Faddan NH1, Sayh KI, Shams H,BH, Myocardial dysfunction in malnourished children., Annals of Pediatric Cardiology, 3 (2), 113-118, July, 2010
49 - Eman.Mosad,Khaled Elsayh,Azza A. Eltayeb., Tissue Factor Pathway Inhibitor and P-Selectin as Markers of Sepsis-Induced Non-overt DIC, Clin Appl Thrombosis, 8, 2009
50 - Kamal M Zahran, Ahmed Y Shahin, Mohamad S Abdellah, Khalid I Elsayh, Sublingual versus vaginal misoprostol for induction of labor at term: a randomized prospective placebo-controlled study., Journal of Obstetrics and Gynaecology Research , December, 2009
51 - Rabie H, Elsayh IK, Zahran AM. , Re-evaluation of Primary Congenital Hypothyroidism using Tc-99m Thyroid Scan. , Alexandria Journal of Pediatrics. , 2007

Supervisions :

1- Naglaa Alm El-din Abd El-rahman, Recent advances in gaucher disease, M. Sc, 22 February 2012
Supervisors : Amal Abdel-Salam Soliman,Khaled Ibrahim Abdel-Rahman
2- Ahmed Ismail Sedik Mohammed, Flu in Children, M. Sc, 1 January 2011
Supervisors : Salah-Eldin Amry Ahmed,Khalid Ibrahim Abd El-Rahman
3- Zeinab Mohammed Ahmed, Carrier Detection in Genetic Diseases, M. Sc, 26 June 2011
Supervisors : Amal Abd EL-Salam Soliman,Khalid Ibrahim Abd EL-Rhaman
4- Ahmed Mofty Abdel - Rady, Gastrointestinal motility disorders in children, M. Sc, 27 December 2010
Supervisors : Naglaa mustafa abdel - hafez,Khaled Ibrahium abdel - rahman
5- Eiman Abdul-Haii Fathi Soliman , Management of Nutritional Anemia, M. Sc, 22 July 2014
Supervisors : Ahmed Gad EL-Rab Askar, Khaled Ibrahim Abdelrahman Elsayh
6- Doa,a mamdoh mohammed, Evidence based management of bronchiolitis , M. Sc, 10 November 2014
Supervisors : dr-Asmaa hamed sheret dr-khaled elsaeh
7- Manar Mohamed Sayed Ahmed, Auditing nursing care for children recieving blood transfusion at Assiut university children hospital, M. Sc, 25 July 2019
Supervisors : prof. Eman Sayed ahmed prof. Khaled Ibrahim El Sayeh dr. Franca Ali Ahmed
Number of courses0 course