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Prof. Mohamed Ali Attia Shafie

Professor, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University

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Current Address

:

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Office Tel.

:

031264

Home Tel.

:

088/2335156

Mobile No.

:

01112727999

E-Mail

:

mohamed.shafei@pharm.aun.edu.eg
mohamedshafie@yahoo.com

google scholar link

:

http://scholar.google.com.eg/citations?user=R4y6FwoAAAAJ&hl=en
Educational Qualifications:
  • Ph. D. In Pharmaceutical Sciences ( Pharmaceutics ) , First Medical Institute, Moscow, the Soviet Union, 1978
  • M. Sc. In Pharmaceutical Sciences, Faculty of Pharmacy, Assiut University, 1973
  • B. Sc. In Pharmacy and Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, 1969


 

 
  • Professor, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 2006
  • Professor, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 1986
  • Associate Professor, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 1982
  • Lecturer, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 1978
  • Assistant Lecturer, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 1973
  • Demonstrator, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 1969
 

Past Positions :

  • Head, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, from August 2002 to September 2006
  • Head, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, from September 1987 to February 1990
  • Head, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, from February 1984 to August 1984
  • Research fields:
    Polymers , Timolol Maleate Ocular , vivo Evaluation , vitro

    Publications:

    1 - Basma N. Abd El-Hamid, Nitin K.Swarnakar, Ghareb M. Soliman, Mohamed A. Attia and Giovanni M. Pauletti, High Payload Nanostructured Lipid Carriers Fabricated with Alendronate/Polyethyleneimine Ion Complexes, International Journal of Pharmaceutics, Vol. 535, No. 1–2, pp. 148-156, https://doi.org/10.1016/j.ijpharm.2017.10.064, 2018
    2 - Mohamed A. Safwat, Ghareb M. Soliman, Douaa Sayed, Mohamed A. Attia, Gold Nanoparticles Capped with Benzalkonium Chloride and Poly (ethylene imine) for Enhanced Loading and Skin Permeability of 5-Fluorouracil, Drug Development and Industrial Pharmacy, DOI: 10.1080/03639045.2017.1339082 , Vol. 43, No. 11, pp. 1780-1791, https://doi.org/10.1080/03639045.2017.1339082, 2017
    Full text
    3 - Mohamed A. Safwat, Ghareb M. Soliman, Douaa Sayed, Mohamed A. Attia, Gold Nanoparticles Enhance 5-Fluorouracil Anticancer Efficacy Against Colorectal Cancer Cells , International Journal of Pharmaceutics , Elsevier, Vol. 513, pp. 648-658, http://www.sciencedirect.com/science/article/pii/S037851731630922X, 2016
    Full text
    4 - Nermin E. Eleraky, Dina F. Mohamed, Mohamed A. Attia, and Giovanni M. Pauletti, Hydrophobic Ion-Pairing of Low Molecular Weight Heparin with Cetyltrimethyl ammonium Bromide." , . International Journal of Pharma Sciences and Research (IJPSR), 6: , 558-565, March, 2015
    5 - Basma N. AbdEl-Hamida,b, Ghareb M. Solimanb, Mohamed A. Attiab and Giovanni M. Paulettia,*, An Ion Pairing Approach to Enhance Oral Bioavailability of Alendronate, JSRR, 2015
    6 - Basma N. AbdEl-Hamid, Ghareb M. Soliman, Mohamed A. Attia and Giovanni M. Pauletti, An Ion Pairing Approach to Enhance Oral Bioavailability of Alendronate, Journal of Scientific Research and Reports, DOI: 10.9734/JSRR/2015/13975, Vol. 5, No. 4, pp. 344-351, 2015
    7 - Ghareb M. Soliman, Mohamed A. Attia, Ramadan A. Mohamed, Poly (Ethylene Glycol)-Block-Poly(ε-Caprolactone) Nanomicelles for the Solubilization and Enhancement of Antifungal Activity of Sertaconazole, Curr. Drug Deliv., DOI: 10.2174/1567201811666140605151923, Vol. 11, No. 6, pp. 753-762, 2014
    8 - Mohamed Ali Attia Shafie, Hadeel Hamdy Mohammed Fayek, Formulation and Evaluation of Betamethasone Sodium Phosphate Loaded Nanoparticles for Ophthalmic Delivery, J. Clin. Exp. Ophthalmol., http://dx.doi.org/10.4172/2155-9570.1000273, Vol. 4, No. 2, 273, pp. 1-11, 2013
    9 - Radwa A. Mohamed, Haidy A. Abass, Mohamed A. Attia, Ola A. Heikal, Formulation and Evaluation of Metoclopramide Solid Lipid Nanoparticles for Rectal Suppository, Journal of Pharmacy and Pharmacology, doi: 10.1111/jphp.12136, Vol. 65, pp. 1607-1621, 2013
    10 - Mohamed Ali Attia Shafie, Mai Ahmed Hassan Rady, In vitro and In vivo Evaluation of Timolol Maleate Ocular Inserts Using Different Polymers, J. Clin. Exp. Ophthalmol., http://dx.doi.org/10.4172/2155-9570.1000246, Vol. 3, No. 8, 246, pp. 1-9, 2012
    11 - Mohamed A. Attia, Mohamed El-Azizi, Mohamed S. Hashish, Design and Evaluation of Ciprofloxacin Hydrochloride Ocular Inserts, Int. J. PharmTech. Res., Vol. 3 (3), pp. 1750-1763, 2011
    12 - Mohamed Attia, Heba Y. El Badawy, Film Forming Gel for Treatment of Oral Mucositis: In-vitro Studies, International Journal of Drug Delivery, doi:10.5138/ijdd.2010.0975.0215.02043, Vol.  2, pp. 314 - 321, 2010
    13 - Muhammad M. Shahwan, Mohammad A. Kobeisy, Muhammad Attia, Fawzia Habib, Gihan Fetih and Akira Yamamoto , 16. Clinical evaluation of oral insulin formulation in type-2 diabetic patients. , Assiut Med. J. , Vol. (31), No.,(2), May , May, 2007
    14 - F.S. Habib m Attia Gihan Fetieh, 17. Excellent absorption enhancing characteristics of No Donors for improving the intestinal absorption of poorly absorbable compound compared with conventional absorption enhancers. , Drug Metab. Pharmacokinet. , Vol. 21(3), June 2006., June, 2006
    15 - F.S. Habib M.Attia Gihan Fetieh, 18. Colon-Specific delivery and enhanced colonic absorption of [Asu1,7]-eel calcitonin using chitosan capsules containing various additives. , J. of Drug Targeting, , 14(3), , 165-172,, 2006
    16 - F.S. Habib M Attia Gihan Fetieh, Improvement of absorption enhancing effects of n-dodecyl-β-D- maltopyranoside by its colon-specific deliver using chitosan capsules. , Int. J. of Pharmaceutics, 293, , 127-135, , 2005
    17 - F. S. Habib M Attia Gihan Fetieh, Nitric oxide donors can enhance the intestinal transport and absorption of insulin and [Asu1,7]-eel calcitonin in rats. , J. of Controlled Release , 106, , 287-297, , 2005
    18 - Attia, M.A., El-Gibaly, I., Shaltout, S.E. and Fetih,G.N.,, Transbuccal permeation, anti-inflammatory activity and clinical efficacy of piroxicam formulated in different gels, , In. J. Pharm., , 276, , 11-28 , 2004
    19 - Abd-Elmageed, A.; Attia, M.A.; Masoud A.A.; Abd-Elotaleb, M.E.:, Performance of propranolol hydrochloride ophthalmic preparations in the eye of human patients. , Mans. J. Pharm. Sci., , 14(1): , 129-142 , 1998
    20 - Attia, M.A. F.S.Habib, Ocular Bioavailability of Prednisolone Multiple Emulsion Delivery Systems . , Bull. Pharm. Sci. Assiut Univ., , Vol. 17, Part 2, , 1995
    21 - Attia, M.A.; Kassem, M.A.; Safwat S.M.; El-Mahdy, M.M.:, Influence of the phase volume ratio of multiple emulsions on the ocular activity of prednisolone. , J.S.T.P. Pharma Sciences. , 5(4) , 309-315, 1995., 1995
    22 - Attia, M.A.; Kassem, M.A.; Safwat S.M.; El-Mahdy, M.M.: , Preparation and evaluation of Hydrocortisone Multiple emulsions in rabbits eye. , J. die Pharm. Ind. , 56(6), , 584 - 588, , 1994
    23 - Attia, M.A.; Kassem, M.A.; Safwat S.M.; El-Mahdy, M.M.: , The formulation-performance relationship of multiple emulsions and ocular activity. , J. of controlled release. , 32, , 259 - 268, , 1994
    24 - Attia, M.A.; Habib, F.S.; Mohamed, A.A.; El-Badry, M.:, In-vitro release and in-vivo performance of propranolol hydrochloride from ophthalmic gels. , Int. Conf. Pharm. Ind., Abs. Book 30, May (1990), Alexandria-Egypt., 1990
    25 - Attia, M.A.; Habib, F.S.; Mohamed, A.A.; El-Badry, M.:, In-vitro and in-vivo studies on propranolol hydrochloride ophthalmic solutions. , Int. Conf. Pharm. Ind., Abs. Book 30, May (1990), Alexandria-Egypt., 1990
    26 - Attia, M.A.; Habib, F.S.; Ka ssem, M.A.; Mohamed, A.A.:, Refinement of Current Theories Underlying the me chanisms of action of viscolizers in ophthalmic preparations. , 16 th inter. Symposium on controlled release of Bioactive Materials, Chicag o, Illinois, U.S.A., 1989. , 1989
    27 - Attia, M.A.; Habib, F.S.; Ka ssem, M.A.; Mohamed, A.A.:, Effect of phenylephrine hydrochloride on betamethasone side effect in relation to viscosity of ophthalmic preparati ons. I. Viscous Solutions. . , Drug Development and Industrial Pharmacy, , 15(2),, 1989
    28 - Attia, M.A.; Habib, F.S.; Kassem, M.A.; Mohamed, A.A.:, Effect of phenylephrine hydrochloride on betamethasone side effect in relation to viscosity of ophthalmic preparations. II. Gel State. , Drug Development and Industrial Pharmacy, , 15(2), , 1989
    29 - Attia, M.A.; Kassem, M.A.; Safwat, M.S.:, In-vitro and In-vitro release of C-Mofebutazone from ocular polymeric inerts. , 16th Inter. Symposium on controlled Release of Bioactive Materials, Chicago, Illinois, U.S.A., 1989., 1989
    30 - Attia, M.A.; Habib, F.S.; Kassem, M.A.; Mohamed, A.A.:, Influence of phenylephrine hydrochloride on the anti-inflmmatory effect of betamethasone in the eye of rabbit. , 15th inter. Symp. on Controlled Release of Bioactive Materials. Basel-Switzerland, August, 1988., 1988
    31 - Attia, M.A.; Kassem, M.A.; Safwat, S.M.:, Impact of formulation factors on Pharmacokinetics of H-dexamethasone in ocular tissues. , 15th Inter. Symp. On controlled release of bioactive materials. Basel-Switzerland, August, 1988., 1988
    32 - Attia, M.A.; Kassem, M.A.; Safwat, S.M.:, In-vivo performance of H-dexamethasone ophthalmic film delivery system in rabbit eye. , Inter. J. of Pharmaceutics, , 47 , 21 - 30., 1988
    33 - Attia, M.A.; Habib, F.S.; Kassem, M.A.; Mohamed, A.A.:, In-vivo performance of opththalmic preparations of betamethasone and phenylephrine hydrochl oride in the rabbit eye. II. Effect of methylhydroxyethylcellulose. , Drug Development and Industrial Pharmacy, , 13(8), , 1987
    34 - Attia, M.A.; Habib, F.S.; Kassem, M.A.; Mohamed, A.A.:, In-vivo performance of ophthalmic solutions of betamethasone and phenylephrine hydrochloride in the eye of rabbit. I.Effect of Methylcellulose. , J. Drug Development and Industrial Pharmacy,, , 13(8), 1987
    35 - F.S. Habib, M.A. Attia and S.M. El-Shanawany, In-vitro Study of Physostigmine Salicylate and Pilocarpine Hydrochloride Release from Different Gel Formulations. , Die Pharmazie Industrie, , 41, , 124-125, , 1986
    36 - Attia, M.A.; Habib, F.S.:, Effect of polyol type onthe In-vitro release of prednisolone from oil-in-water type ointment. , J. Pharm. Ind., , 48(11), , 1986
    37 - Attia, M.A.; Habib, F.S.; Kassem, M.A.; Mohamed, A.A.:, In-vivo performance of ophthalmic prep arations of betamethasone and phenylephrine hydrochloride in the rabbit eye:Effect of polyvinyl alcohol. , Pharmaceutical Research. , 3(4), , 1986
    38 - Attia, M.A.; Habib, F.S.; Kassem, M.A.; Mohamed, A.A.:, In-vitro release study of betamethasone and phenylephrine hydrochloride from ophthalmic preparations. . , Int. J. of Pharmaceutics, , 29, , 1986
    39 - Attia, M.A.; Habib, F.S.; Kassem, M.A.; Mohamed, A.A.:, Activity of ophthalmic gels of betamethasone and phenylephrine hydrochloride in the rabbits eye. , Int. J. Pharmaceutics, , 32, , 1986
    40 - Attia, M.A.; Habib, F.S., Pilocarpine delivery from multiple emulsions. , J. S.T.P. Pharma, , , 2(18), 1986
    41 - Attia, M.A.; Habib, F.S., Ocular delivery of pilocarpine hydrochloride from water soluble polymeric inserts. , Acta Pharm. Technol. , 32(3), , 1986
    42 - Attia, M.A.; Habib, F.S.:, Permeability of phenylephrine hydrochloride through the cornea of rabbits. , J. de Pharmazeutische Industrie, , 48(11), , 1986
    43 - Attia, M.A.; El-Sourady, H.A.; El-Shanawany, S.M.:, Release and rheological characteristics of chloramphenicol ophthalmic ointments. , J. Pharm. Ind., , 48(10), , 1986
    44 - Attia, M.A.; Kassem, M.A.; Safwat, S.M.:, Effect of formulation variables on the permeation of dexamethasone through different polymeric films. I. Effect of different polymer type and plasticizers. , J.S.T.P. Pharma,, 2(12), , 1986
    45 - Attia, M.A.; Kassem, M.A.; Safwat, S.M.:, Effect of formulation variables on the permeation of dexamethasone through different polymeric films. II. Effect of different surfactants. , J.S.T.P. Pharma, , 2(13), , 1986
    46 - Attia, M.A.; Kassem, M.A.; Safwat, S.M.:, In-vitro release of dexamethasone from polymeric inserts. , J. Pharm. Belg. , 41(2), , 1986
    47 - M.A. Attia, H.A. El-Sourady and S.M. El-Shanawany, Vehicle Influence on Ocular Disposition of Chlortetracycline Hydrochloride and Chloramphenicol in Albino Rabbit. , Acta Pharm. Techn., , 31 (2), , 1985
    48 - F.S. Habib, M.A. Attia and S.M. El-Shanawany, Effect of Different Ointment Bases on Ocular Disposition of Ethylphenylephrine in Rabbit Eyes. , International Journal Pharmacetuics, , 26, , 243-249, , 1985
    49 - F.S. Habib, M.A. Attia and S.M. El-Shanawany, Ocular Bioavailability of Pilocarpine Hydrochloride in Combination with Physostigmine Salicylate from Different Gel Formulations. . , Acta Pharm. Chem., , 13, , 33-38, , 1985
    50 - Attia, M.A.; Habib, F.S.:, Dissolution rates of Carbamazepine and Nitrazepam utilizing sugar solid dispersion system. , Drug Devel. and Ind. Pharmacy, , 11(11), , 1985
    51 - Attia, M.A.; Habib, F.S.:, Effect of particle size on dissolution rate of monophenylbutazone solid dispersion in presence of certain additives. , Drug Devel. and Ind. Pharmacy, , 11(11), , 1985
    52 - Attia, M.A.; El-Sourady, H.A.; El-Shanawany, S.M.: , Vehicle influence on ocular disposition of chlortetracycline hydrochloride and chloramphenicol in albino rabbit. , Acta Pharmaceutica Technologica, , 31(2), , 1985
    53 - Attia, M.A.; Habib, F.S.; El-Shanawany, S.M.:, Ocular bioavailability of pilocarpine hydrochloride in combination with physostigmine salicylate from different gel formulations. , Arch. Pharm. Chem. Sci. Ed., , 13, 1985
    54 - Attia, M.A.; El-Sourady, H.A.; El-Shanawany, S.M.: , Stability of chlortetracycline hydrochloride and chloramphenicol in some ophthalmic ointment bases. J. Die. , Pharmazie, , 40, H. 9, , 1985
    55 - Attia, M.A.; Habib, F.S.:, Comparative study of the ocular activity in rabbit eyes of adrenaline bitartrate formulated in carbopol and poloxamer gels. , Arch. Pharm. Chem. Sci. Ed., , 12, , 1984
    56 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, Effect of different disintegrants on the availability of directly compressed sulfadimidine tablets. , J. Die Pharmazie,, , 38, H-7, 1983
    57 - Attia, M.A.; Habib, F. S.; Aboutaleb, A.E.:, Effect of certain organic and inorganic additives on the flocculation of suspensions containing different sulfonamides. , Bull. Pharm. Sci., Assiut, , Vol. 6, , 1983
    58 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, Study on the dissolution of diazepam from its solid dispersion and coprecipitates in the presence of various concentrations of non-ionic surfactants. , J. Die Pharmazie,, , 37, H-4, 1982
    59 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, Dissolution study on sulfisoxazole, sulfapyridine and sulfamerazine from their solid dispersions and coprecipitates. , Bull. Pharm. Sci., Assiut, , 1982
    60 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, Effect of directly compressible vehicles on the uniformity of contents of oxytetracycline hydrochloride tablets. , Bull. Pharm. Sci., Assiut, , Vol. 5, , 1982
    61 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, Effect of certain ophthalmic preparations containing pilocarpine hydrochloride and dexamethasone on the intraocular pressure of rabbits eye. , Bull. Pharm. Sci., Assiut, , Vol. 5,1982, 1982
    62 - H.A. El-Sourady, M.A. Attia and S.M. El-Shanawany, Release and Rheological Characteristics of Chlortetracycline Hydrochloride Ophthalmic Ointments. , Bull. Pharm. Sci., Assiut University, , 14, 1981
    63 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, A study on the release of prednisone from new ointment bases containing various additives. , J. Die Pharmazie,, 36(1), , 1981
    64 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, Effect of micellar structure on the solubility of prednisone and prednisolone. , Indian J. of Pharmacy, , 43(1), , 1981
    65 - Attia, M.,A.; Habib, F.S.; Aboutaleb, A.E.:, Effect of certain additives on the solubilization of dexamethasone. , J. Drug Research, Egypt, , 13(1-2), , 1981
    66 - Attia, M.A.; Habib, F.S.; Aboutaleb, A.E.:, Effect of surfactant structure on the release of dexamethasone from different ointment bases. , Bull. Of Pharm. Sci. Assiut , (3), , 1980
    67 - S.A. Ibrahim, A.A. Kassem, I.A. Attia and S. Ismail,, Studies on the solubility of rifampicin. II. Effect of some aromatic monocarboxylic acids sodium salts nicotinamide and isoniazide on the water solubility of rifampicin. , Bull. Pharm. Sci., Assiut University,, 3, , 41-58 , 1980
    68 - A.A. Kassem, S.A. Ibrahim, I.A. Attia and S. Ismail, , Factors affecting rifampicin stability in ointments. , Ind. J. Pharm. Sci., , 42, , 84-86 , 1980
    69 - S.A. Ibrahim, A.A. Kassem, I.A. Attia and S. Ismail,, Studies on the solubility of rifampicin. I. Effect of co-solvents and nonionic surfactants on the solubility of rifampicin. , Bull. Pharm. Sci., Assiut University, , 2, , 1-10 . , 1979
    70 - S.A. Ibrahim, A.A. Kassem, I.A. Attia and S. Ismail,, Studies on some factors affecting the stability of rifampicin in solutions. , Bull. Pharm. Sci., Assiut University, , 2, , 11-25 , 1979
    71 - Sina, A.; Youssef, M.K.; Kassem, A.A.; Attia, M.A.:, Effect of Sorption and Leaches of Plastic Granules on the stability of antimicrobial agents and antioxidants. ., Indian, J. Pharmacy, , 35(2), , 1973
    72 - Sina, A.; Youssef, M.K.; Kassem, A.A.; Attia, M.A.:, Leaches and Water Sorption of Polyethylene and Polyvinyl chloride. , Indian, J. Pharmacy, , 34(4), , 1972

    Supervisions :

    1- Nivin Abdel-Azim Abdel-Rahim, Correlation Between The Effect of Different High Doses of Methotrexate and its Therapeutic Efficacy in Leukemia and Lymphoma among Children, M. Sc, 29 October 2006
    Supervisors : Mahmoud Mohamed El-Merzabani, Mohamed Ali Attia, Salah Saleh Abd El- Hadi
    2- Jihan Nabil Hassan, Formulation and Evalualtion Studies on Buccal Gels Containing Piroxicam, M. Sc, 20 February 2000
    Supervisors : Mohamed Ali Attia, Ibrahim Elsayed al-Jabali, Salah al-Din Jaber Shaltout
    3- Gihan Nabil Hassan Fetih, Studies on Oral Delivery of Certain Peptide Derivatives, Ph. D., 27 April 2005
    Supervisors : Mohamed Ali Attia, Fawzia Sayed Ahmed Habib, Akira Yamamoto
    4- Abd-Elrazak Abd-Elmageed Mohamed , Biopharmaceutic Study Of Certain Corticosteroid And Phenylephrine Hydrochloride In Ophthalmic Preparations, Ph. D., 30 June 1985
    Supervisors : Mahfouz Abd El-Maged Kassem, Mohamed Ali Attia, Fawzia Sayed Habib.
    5- Gihan Nabil Hassan Fetih, Formulation and evaluation studies on buccal gels containing piroxicam, M. Sc, 13 January 2000
    Supervisors : Mohamed Ali Attia, Salah El-Dein Gaber Shaltout, Ibrahim El-Sayed El-Gibaly
    Number of courses0 course