Dr. Ghareb Mohamed Abdel-Aal Soliman

Associate Professor, Department of Pharmaceutics , Faculty of Pharmacy, ِِAssiut University

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Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Educational Qualifications:
  • Ph. D. In Pharmaceutical Sciences ( Pharmaceutics ) , University of Montreal, Canada, 2010
  • M. Sc. In Pharmaceutical Sciences ( Pharmaceutics ) , Faculty of Pharmacy, Assiut University, 2003
  • B. Sc. In Pharmaceutical Sciences, Faculty of Pharmacy, Assiut University, 1998
  • Associate Professor, Department of Pharmaceutics , Faculty of Pharmacy, ِِAssiut University, 2015
  • Lecturer, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 2010
  • Assistant Lecturer, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 2003
  • Demonstrator, Department of Pharmaceutics , Faculty of Pharmacy, Assiut University, 1998

Past Positions :

  • Director of Information Technology unit, from October 2013 to June 2014
  • Research fields:
    Drug delivery systems , Pharmaceutical Technology


    1 - W. Faisal, G.M. Soliman and A. M. Hamdan, Enhanced Skin Deposition and Delivery of Voriconazole Using Ethosomal Preparations, J. Liposome Res., DOI: 10.1080/08982104.2016.1239636, Vol. 28, No. 1, pp. 14-21, 2018
    2 - Hassan A.S., Soliman G.M., El-Mahdy M.M. and El-Gindy G.E.A., Solubilization and Enhancement of Ex Vivo Vaginal Delivery of Progesterone Using Solid Dispersions, Inclusion Complexes and Micellar Solubilization, Curr. Drug Deliv., DOI: 10.2174/1567201814666170320142136, Vol. 15, No. 1, pp. 110-121, 2018
    3 - Hassan A.S., Soliman G.M., Ali M.F., El-Mahdy M.M. and El-Gindy G.E.A., Mucoadhesive Tablets for the Vaginal Delivery of Progesterone: In Vitro Evaluation and Pharmacokinetics/Pharmacodynamics in Female Rabbits, Drug. Dev. Ind. Pharm., DOI: 10.1080/03639045.2017.1386203, Vol. 44, No. 2, pp. 224-232, 2018
    4 - Basma N. Abd El-Hamid, Nitin K.Swarnakar, Ghareb M. Soliman, Mohamed A. Attia and Giovanni M. Pauletti, High Payload Nanostructured Lipid Carriers Fabricated with Alendronate/Polyethyleneimine Ion Complexes, International Journal of Pharmaceutics, Vol. 535, No. 1–2, pp. 148-156,, 2018
    5 - Mohamed A. Safwat, Ghareb M. Soliman , Douaa Sayed and Mohamed A. Attia , Fluorouracil-Loaded Gold Nanoparticles for the Treatment of Skin Cancer : Development, in Vitro Characterization, and in Vivo Evaluation in a Mouse Skin Cancer Xenograft Model, Molecular Pharmaceutics, DOI: 10.1021/acs.molpharmaceut.8b00047 , ACS , Vol. 15 , No. 6, pp. 2194-2205, July, 2018
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    6 - Ghareb M. Soliman, Gihan Fetih, Ahmed M. Abbas, Thermosensitive Bioadhesive Gels for the Vaginal Delivery of Sildenafil Citrate: In Vitro Characterization and Clinical Evaluation in Women Using Clomiphene Citrate for Induction of Ovulation, Drug Development and Industrial Pharmacyو DOI: 10.1080/03639045.2016.1254239, Vol. 43, No. 3, pp. 399-408,, 2017
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    7 - Mohamed A. Safwat, Ghareb M. Soliman, Douaa Sayed, Mohamed A. Attia, Gold Nanoparticles Capped with Benzalkonium Chloride and Poly (ethylene imine) for Enhanced Loading and Skin Permeability of 5-Fluorouracil, Drug Development and Industrial Pharmacy, DOI: 10.1080/03639045.2017.1339082 , Vol. 43, No. 11, pp. 1780-1791,, 2017
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    8 - G.M Soliman, Nanoparticles as Safe and Effective Delivery Systems of Antifungal Agents: Achievements and Challenges, Int. J. Pharm., DOI: 10.1016/j.ijpharm.2017.03.019, Vol. 523, No. 1, pp. 15-32, 2017
    9 - Helmy A.M., Elsabahy M., Soliman G.M., Mahmoud M.A. and Ibrahim E.A, Development and In Vivo Evaluation of Chitosan Beads for the Colonic Delivery of Azathioprine for Treatment of Inflammatory Bowel Disease, Eur. J. Pharm. Sci., DOI: 10.1016/j.ejps.2017.08.025, Vol. 109, pp. 269-279, 2017
    10 - Tawfeek H.M., Faisal W. and Soliman G.M., Enalapril Maleate Orally Disintegrating Tablets: Tableting and In Vivo Evaluation in Hypertensive Rats, Pharm. Dev. Technol., DOI: 10.1080/10837450.2017.1329318, pp. 1-8,, 2017
    11 - Hytham H Gadalla, Ibrahim El-Gibaly, Ghareb M Soliman, Fergany A Mohamed, Ahmed M El-Sayed, Amidated Pectin/Sodium Carboxymethylcellulose Microspheres as a New Carrier for Colonic Drug Targeting: Development and Optimization by Factorial Design, Carbohydrate Polymers , Elsevier, Vol. 153, pp. 526-534,, 2016
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    12 - Mohamed A. Safwat, Ghareb M. Soliman, Douaa Sayed, Mohamed A. Attia, Gold Nanoparticles Enhance 5-Fluorouracil Anticancer Efficacy Against Colorectal Cancer Cells , International Journal of Pharmaceutics , Elsevier, Vol. 513, pp. 648-658,, 2016
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    13 - Dina Fathalla, Ghareb M. Soliman, Ehab A. Fouad, Development and In vitro / In vivo Evaluation of Liposomal Gels for the Sustained Ocular Delivery of Latanoprost, Journal of Clinical and Experimental Ophthalmology , vol. 6, pp. 219-226, 10.4172/2155-9570.1000390 , 2015
    14 - Basma N. AbdEl-Hamida,b, Ghareb M. Solimanb, Mohamed A. Attiab and Giovanni M. Paulettia,*, An Ion Pairing Approach to Enhance Oral Bioavailability of Alendronate, JSRR, 2015
    15 - Hytham H. Gadalla, Ghareb M. Soliman, Fergany A. Mohammed, Ahmed M. El-Sayed, Development and In Vitro/In Vivo Evaluation of Zn-pectinate Microparticles Reinforced with Chitosan for the Colonic Delivery of Progesterone, Drug Delivery, DOI: 10.3109/10717544.2015.1028602, Informahealthcare, Vol. 23, No. 7, pp. 2541-2554,, April, 2015
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    16 - Shaaban K. Osman, Ghareb M. Soliman, Saleh Abd El Rasoul, Physically Cross-Linked Hydrogels of β-Cyclodextrin Polymer and Poly(ethylene glycol)-cholesterol as Delivery Systems for Macromolecules and Small Drug Molecules, Current Drug Delivery, DOI: 10.2174/1567201812666150326113331 , Vol. 12, No. 4, pp. 415-424, 2015
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    17 - Ghareb M. Soliman, Shaaban K. Osman and Ahmed M. Hamdan, Preparation and Evaluation of Anthralin Biodegradable Nanoparticles As a Potential Delivery System for the Treatment of Psoriasis, International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 7, No. 12, pp. 36-40, 2015
    18 - Basma N. AbdEl-Hamid, Ghareb M. Soliman, Mohamed A. Attia and Giovanni M. Pauletti, An Ion Pairing Approach to Enhance Oral Bioavailability of Alendronate, Journal of Scientific Research and Reports, DOI: 10.9734/JSRR/2015/13975, Vol. 5, No. 4, pp. 344-351, 2015
    19 - Ghareb M. Soliman, Anjali Sharma, Yiming Cui, Rishi Sharma, Ashok Kakkar, Dusica Maysinger, Miktoarm Star Micelles Containing Curcumin Reduce Cell Viability of Sensitized Glioblastoma, J. Nanomed. Biotherapeutic Discov., DOI: 10.4172/2155-983X.1000124, Vol. 4, No. 2, pp. 1-10, 2014
    20 - Ghareb M. Soliman, Yu Ling Zhang, Geraldine Merle, Marta Cerruti, Jake Barralet, Hydrocaffeic Acid–Chitosan Nanoparticles with Enhanced Stability, Mucoadhesion and Permeation Properties, Eur. J. Pharm. Biopharm., DOI: 10.1016/j.ejpb.2014.09.003, Vol. 88, No. 3, pp. 1026-1037, 2014
    21 - Shabaan Osman, Ghareb M. Soliman, Mohamed Amin, Alaa Zaky, Self-Assembling Hydrogels Based on β-Cyclodextrin Polymer and Poly (Ethylene Glycol) Bearing Hydrophobic Moieties for Protein Delivery, Int. J. Pharm. Pharm. Sci., Vol. 6, No. 7, pp. 591-597,, 2014
    22 - Ghareb M. Soliman, Mohamed A. Attia, Ramadan A. Mohamed, Poly (Ethylene Glycol)-Block-Poly(ε-Caprolactone) Nanomicelles for the Solubilization and Enhancement of Antifungal Activity of Sertaconazole, Curr. Drug Deliv., DOI: 10.2174/1567201811666140605151923, Vol. 11, No. 6, pp. 753-762, 2014
    23 - Ghareb M. Soliman, Rocio Redon, Anjali Sharma, Diana Mejía, Dusica Maysinger, Ashok Kakkar, Miktoarm Star Polymer Based Multifunctional Traceable Nanocarriers for Efficient Delivery of Poorly Water Soluble Pharmacological Agents, Macromol. Biosci., DOI: 10.1002/mabi.201400123, Vol. 14, No. 9, pp. 1312-1324, 2014
    24 - Hytham H. Gadalla A. M. El-Sayed Fergany A. M. I. El-Gibaly Ghareb M. Soliman, Chitosan Microspheres as Potential Carriers For Colon Targeting, Bulletin of Pharmaceutical Sciences , Assiut University Press, 37 (2), 117-127, December, 2014
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    25 - Hytham H. Gadalla I. El-Gibaly Ghareb M. Soliman Fergany A. Mohamed Ahmed M. El-Sayed, Pectin/ NaCMC microparticles as a new carrier for colon targeting of Progesterone, 9th Pharmaceutical Sciences Conference, Faculty of Pharmacy, Assiut, Egypt, March, 2014
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    26 - Sebastien Boridy, Ghareb M. Soliman, Dusica Maysinger, Modulation of Inflammatory Signaling and Cytokine Release from Microglia by Celastrol Incorporated into Dendrimer Nanocarriers, Nanomedicine, Vol. 7, No. 8, pp. 1149-1165, 2012
    27 - Anjali Sharma, Ghareb M. Soliman, Noura Al-Hajaj, Rishi Sharma, Dusica Maysinger, Ashok Kakkar, Design and Evaluation of Multifunctional Nanocarriers for Selective Delivery of Coenzyme Q10 to Mitochondria, Biomacromolecules,, Vol. 13, pp. 239-252 , 2012
    28 - Jinke Xu, Ghareb M. Soliman, Jake Barralet, Marta Cerruti, Mollusk Glue Inspired Mucoadhesives for Biomedical Applications, Langmuir, doi: 10.1021/la3025414, Vol. 28 - No.39, pp. 14010-7, 2012
    29 - Noura A. Al-Hajaj, Alexandre Moquin, Kevin D. Neibert, Ghareb M. Soliman, Francoise M. Winnik, Dusica Maysinger, Short Ligands Affect Modes of QD Uptake and Elimination in Human Cells, ACS Nano, Vol. 5, No. 6, pp. 4909-4918, 2011
    30 - Ghareb M. Soliman, Anjali Sharma, Dusica Maysinger, Ashok Kakkar, Dendrimers and Miktoarm Polymers Based Multivalent Nanocarriers for Efficient and Targeted Drug Delivery, Chemical Communications, doi:10.1039/C1CC11981H, Vol. 47, pp. 9572-9587, 2011
    31 - Ghareb M. Soliman, Rishi Sharma, Angela O. Choi, Sunil K. Varshney, Françoise M. Winnik, Ashok K. Kakkar, Dusica Maysinger, Tailoring the Efficacy of Nimodipine Drug Delivery using Nanocarriers Based on A2B Miktoarm Star Polymers, Biomaterials, doi:10.1016/j.biomaterials.2010.07.039, Vol. 31, pp. 8382-8392, 2010
    32 - Ghareb Mohamed Soliman, Angela O. Choi, Dusica Maysinger, Françoise M. Winnik, Minocycline Block Copolymer Micelles and their Anti-Inflammatory Effects on Microglia, Macromolecular Bioscience., DOI: 10.1002/mabi.200900259, Vol. 10 No.3, pp. 278-288, 2010
    33 - Ghareb M. Soliman,Janek Szychowski, Stephen Hanessian, Françoise M. Winnik, Robust Polymeric Nanoparticles for the Delivery of Aminoglycoside Antibiotics using Carboxymethyldextran-b-Poly(Ethyleneglycols) Lightly Grafted with n-Dodecyl Groups., Soft Matter., DOI: 10.1039/C0SM00316F, Vol. 6, pp. 4504-4514 , 2010
    34 - Ghareb Mohamed Soliman, Françoise M. Winnik, Enhancement of Hydrophilic Drug Loading and Release Characteristics through Micellization with New Carboxymethyldextran-PEG Block Copolymers of Tunable Charge Density, International Journal of Pharmaceutics, doi:10.1016/j.ijpharm.2007.12.029, Vol. 356, pp. 248-258, 2008
    35 - Oscar Suarez Hernandez, Ghareb Mohamed Soliman, Françoise M. Winnik, Synthesis, Reactivity, and pH-Responsive Assembly of New Double Hydrophilic Block Copolymers of Carboxymethyldextran and Poly(Ethylene Glycol), Polymer, doi: 10.1016/j.polymer.2006.12.036, Vol.  48, pp. 921-930, 2007
    36 - G. A. El-Gindy, A . M. El-Sayed, A. M. Abdel-Mageed andGh. M. Abdel Aal, Muco-adhesive vaginal tablets of natamycin for vaginal candidiasis, Bull. Pharm. Sci., Assiut Univ. Vol. 26, Part 1, June 2003, PP. 29-40., June, 2003
    37 - G. A. El-Gindy, A. M. El-Sayed, A. M. Abdel-Mageed and Gh. M. Abdel Aal, Formulation and Evaluation of bucco-adhesive natamycin tablets,, Bull. Pharm. Sci., Assiut Univ. Vol. 25, Part 2, December 2002, PP. 125-135., December, 2002

    Supervisions :

    1- Basma Nagy Abdel-Hamid , Rational Design of Nanostructured Lipid Carriers Formulation to Improve Oral Bioavailability of Alendronate ., Ph. D., 14 December 2016
    Supervisors : Prof. Dr. Mohamed Ali Attia Dr. Giovanni M. Pauletti Dr. Ghareb M. Soliman
    2- Mohamed Ahmed Safwat, Development and characterization of gold nanoparticles loaded with 5-fluorouracil ., Ph. D., 8 February 2017
    Supervisors : Prof. Dr. Mohamed Ali Attia Shafie Prof. Dr. Doaa Mohamed Sayed Dr. Gareb Mohamed Abdel-Al

    Awards and Grants :

    1 - " " Pharmaceutics, 2008.
    2 - " the Canadian Chapter of Controlled Release Society " in Medical Sciences, 2011.
    3 - " " in Medical Sciences, 2012.
    4 - " " in Medical Sciences, 2008.
    Number of courses1 course

    Pharmaceutical Dosage Forms ----Faculty of Pharmacy , Department of Pharmaceutics