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Prof. Douaa Mohamed Sayed Hussein

Vice Dean for Graduate Studies and Research، South Egypt Cancer Institute، Assiut University
Professor, Department of Clinical Pathology , South Egypt Cancer Institute, ِِAssiut University

C.V Details




Print copy Member login MIS Data

 

 

Office Tel.

:

04245

Home Tel.

:

20882332016

Mobile No.

:

+201006261987

Fax No.

:

0020882348609

E-Mail

:

douaa@aun.edu.eg
douaa_sayed@hotmail.com

google scholar link

:

https://scholar.google.com.eg/citations?user=R3ZgoakAAAAJ&hl=en&oi=sra
Educational Qualifications:
  • M.D., Faculty of Medicine, Assiut University, 2005


 

 
  • Professor, Department of Clinical Pathology , South Egypt Cancer Institute, ِِAssiut University, 2015
  • Associate Professor, Department of Clinical Pathology , South Egypt Cancer Institute, ِِAssiut University, 2010
  • Lecturer, Department of Clinical Pathology , South Egypt Cancer Institute, Assiut University, 2005
  • Assistant Lecturer, Department of Clinical Pathology , South Egypt Cancer Institute, Assiut University, 2000
  • Demonstrator, Department of Clinical Pathology , South Egypt Cancer Institute, Assiut University, 2000
 

Current Position :

  • Vice Dean for Graduate Studies and Research, South Egypt Cancer Institute, Assiut University, since December 2012
  • Research fields:
    Flow cytometry , Hematology , basic research , Immunology , Oncology

    Publications:

    1 - Ahmed A. Markeb, Nagwa A. El-Maali, Douaa M. Sayed, Amany Osama, Mohamed A. Y. Abdel-Malek, Amen H. Zaki, Mostafa E. A. Elwanis, and James J. Driscoll, Synthesis, Structural Characterization, and Preclinical Efficacy of a Novel Paclitaxel-Loaded Alginate Nanoparticle for Breast Cancer Treatment, International Journal of Breast Cancer, Hindawi Publishing Corporation, Volume 2016 (2016), Article ID 7549372, , 8 pages, 2016
    2 - Mohamed A. Safwat, Ghareb M. Soliman, Douaa Sayed, Mohamed A. Attia, Gold Nanoparticles Enhance 5-Fluorouracil Anticancer Efficacy Against Colorectal Cancer Cells , International Journal of Pharmaceutics , Elsevier, Vol. 513, pp. 648-658, http://www.sciencedirect.com/science/article/pii/S037851731630922X, 2016
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    3 - Asmaa Salah Shaltout, Douaa Sayed, Mohamed Saad Badary, Amany Mohammed Nafee, Mona Hussein El Zohri, Rania Bakry, Shabaan Hashem Ahmed, Effect of IL6 and IL23 on double negative T cells and anti ds-DNA in Systemic lupus Erythematosus Patients, Human Immunology, ELSEVIER, vol: 77 No: 10, 937-43, https://www.ncbi.nlm.nih.gov/pubmed/27343994, October, 2016
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    4 - Mohamed A.Y. Abdel Malek, Sajjeev Jagannathan, Ehsan Malek, Douaa M. Sayed, Sahar A. Elgammal, Hanan G. Abd El-Azeem, Nabila M. Thabet and James J. Driscoll, Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma., Oncotarget. , 2015
    5 - rania bakry,douaa sayed, shereif sayed ,montaser abdel fatah mohamed,naglaa k. idris, the immuno;ogical role monocyte and other cytokines in patients with breast cancer undergoing paravertebral analgesia , comarative clinical pathology, May, 2015
    6 - Mohamed AY Abdel Malek, Sajjeev Jagannathan, Ehsan Malek, Douaa M Sayed, Sahar A Elgammal, Hanan G Abd El-Azeem, Nabila M Thabet, James J Driscoll, Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma, Oncotarget, 2015
    7 - Mohamed A.Y. Abdel Malek1,2,3,*, Sajjeev Jagannathan1,2,*, Ehsan Malek1,2, Douaa M. Sayed4, Sahar A. Elgammal3, Hanan G. Abd El-Azeem3, Nabila M. Thabet3 and James J. Driscoll1,2,5,6, Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma, Oncotarget,, Vol. 6 - No. 5, February, 2015
    8 - Hongkun Wang1, Ying Wang2, Krishna K.Kota2, Bhaskar Kallakury3, Nabiel N.Mikhail4, Douaa Sayed4, Ahmed Mokhtar4, Doaa Maximous4, Etemad H.Yassin4, Iman Gouda5, Adebiyi Sobitan2, Bing Sun2, Christopher A.Loffredo1,2 and Yun-Ling Zheng1,2,*, Strong association between long and heterogeneous telomere length in blood lymphocytes and bladder cancer risk in Egyptian, Carcinogenesis, November, 2015
    9 - Ahmad K. Dyab1, Doaa A. Yones*1, Douaa M. Sayed2, Tasneem M. Hassan1, Detection, Enumeration and Viability Evaluation of Giardia Cysts in Water Samples Using Flow Cytometry, Global Advanced Research Journal of Microbiology , Global Advanced Research Journals, (Vol. 4(6, 077-086, , http://garj.org/garjm, July, 2015
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    10 - Naglaa K. Idriss, Andrew D. Blann,FRCPath, FRCP2, Douaa M. Sayed, Marwa A. Gaber,Hosny A. Hassen, Yehia Taha Kishk, Circulating Endothelial Cells and Platelet Microparticles in Mitral Valve Disease With and Without Atrial Fibrillation, Angiology, pp. 1-7, 8, 2014
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    11 - Azza A. Eltayeb; Faisal-Alkhateeb Ahmad; Douaa M. Sayed; Amany M. Osama, Subclinical vascular endothelial dysfunctions and myocardial changes with type 1 diabetes mellitus in children and adolescents., Pediatric Cardiology , 2014
    12 - Badr G, Sayed D, Maximous D, Mohamed AO, Gul M., Increased susceptibility to apoptosis and growth arrest of human breast cancer cells treated by a snake venom-loaded silica nanoparticles, Cell Physiol Biochem. , 1640-51, 2014
    13 - Azza A. Eltayeb; Douaa M. Sayed; Noha A. Afifi; Maggie A. Ibrahim; Tahra M. Sheref , Regulatory T cell subsets in children with systemic lupus erythematosus., Rheumatology, 1085-1091, 2014
    14 - Douaa Sayed, Omnia H B El-Badawy, Eman Nasr Eldin, Rania Bakry, Mohamed S Badary, Mohamed E Abd-Alrahman, Mohamed A El-Feky, Amany G Thabit, Is Foxp3 A Good Marker for Regulatory T Cells?, THE EGYPTIAN JOURNAL OF IMMUNOLOGY, Vol. 21,No.2, 2014
    15 - Mohamed A. Bakr1, Khaled M. Fares2, Sahar A. Mohamed2, Hesham M. Hamza3, Douaa M. Sayed4, Diab F Hetta2, Effect of protective ventilation on pro-inflammatory cytokine response during one lung ventilation in esophagectomy: a randomized controlled study, SECI Oncology, 1-7, 2014
    16 - Sayed D1, Badrawy H2, Gaber N2, Khalaf MR2., p-Stat3 and bcr/abl gene expression in chronic myeloid leukemia and their relation to imatinib therapy., Leuk Res. , 38(2), 243-250, 2014
    17 - Khaled M. Fares, MD, Sahar A. Mohamed, MD, Hesham M. Hamza, MD, Douaa M. Sayed, MD, and Diab F. Hetta, Msc, Effect of Thoracic Epidural Analgesia on Proinflammatory Cytokines in Patients Subjected to Protective Lung Ventilation During Ivor Lewis Esophagectomy, Pain Physician, Vol 17 NO 4, 305-315, 2014
    18 - Azza A Eltayeb, Douaa M Sayed, Noha A Afifi, Maggie A Ibrahim, Tahra M Sheref, Regulatory T cell subsets in children with systemic lupus erythematosus, Clinical rheumatology, Springer London, Vol.33,No.8, PP.1085-1091, 8, 2014
    19 - N Idriss , M Gaber , D Sayed , H Hassen , Y Kishk , P219Plasma oxidized low density lipoprotein, CD40 and p-selectin levels: relationship to diseases with and without atrial fibrillation, European Society of Cardiology, June, 2014
    20 - Mohamed AY Abdel Malek, Douaa M Sayed, Youseryeia A Ahmad, James J Driscoll, Chronic eosinophilic leukemia transformation into acute myeloid leukemia with monocytic differentiation, Case Reports in Internal Medicine, 2014
    21 - Mohamed AY Abdel Malek, Sajjeev Jagannathan, Ehsan Malek, Nikhil Vad, Douaa M Sayed, Sahar A Elgammal, Hanan G Abd El-Azeem, Nabila M Thabet, James J Driscoll, Novel Therapeutic Strategies to Target Protein Quality Control Compartments in Multiple Myeloma, Blood, 2014
    22 - Sewify EM, Sayed D, Abdel Aal RF, Ahmad HM, Abdou MA, Increased circulating red cell microparticles (RMP) and platelet microparticles (PMP) in immune thrombocytopenic purpura., Thromb Res. , Vol. 131 - No.2, pp. 59 - 63, February, 2013
    23 - Abeer Elkady, Sahar Aboulfotuh, Elsayed Mostafa Ali, Douaa Sayed, Nashwa M Abdel-Aziz, Amany M Ali, Shuko Murakami, Sayuki Iijima, Yasuhito Tanaka, Incidence and characteristics of HBV reactivation in hematological malignant patients in south Egypt, World J Gastroenterol, 7 -19(37), 6214-6220, October, 2013
    24 - Douaa Sayed∗, Hosny Badrawy, Noha Gaber, Muhammed R. Khalaf, p-Stat3 and bcr/abl gene expression in chronic myeloid leukemia and their relation to imatinib therapy, Leukemia Research, 38 (2014), 243-250, October, 2013
    25 - El Makarem MA, Eslam M, Sayed D, Shawkat M, Idriss NK, Soliman EM1, Sherif T, Abdelshaheed R, Abdelhailm H, Sahrawi MA, Elheney S, Diabetes worsening of hepatitis C cirrhosis: are alterations in monocytic tissue factor (CD 142) is the cause?, Ann Hepatol, PP.27-37, February, 2013
    26 - El-Sokkary HG, Sayed MD, Fuad AS and Abdel Shakor AB, Modulation of autophagy enhances the apoptotic cell death in human T lymphoma cells treated with Anthocyanin. , Egypt. Acad. J. Biolog. Sci., Egypt. Acad. J. Biolog. Sci, 5(2), 87-97., www.eajbs.eg.net, April, 2013
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    27 - Abu El Makarem MA, Abdel Hamid M, Abdel Aleem A, Ali A, Shatat M, Sayed D, Deaf A, Hamdy L, Tony EA., Prevalence of occult hepatitis B virus infection in hemodialysis patients from egypt with or without hepatitis C virus infection., Hepat Mon. , Vol. 12 - No.4, pp. 253 - 258, April, 2012
    28 - El-Badawy O, Sayed D, Badary MS, Abd-Alrahman ME, El-Feky MA, Thabit AG., Relations of regulatory T cells with hepatitis markers in chronic hepatitis B virus infection., Hum Immunol. , Vol. 73, No.4, pp. 335 - 341, April, 2012
    29 - Sayed D, Al-Sadoon MK, Badr G., Silica nanoparticles sensitize human multiple myeloma cells to snake (Walterinnesia aegyptia) venom-induced apoptosis and growth arrest., Oxid Med Cell Longev , 2012
    30 - Badr G, Bashandy S, Ebaid H, Mohany M, Sayed D., Vitamin C supplementation reconstitutes polyfunctional T cells in streptozotocin-induced diabetic rats, Eur J Nutr., 8, 2012
    31 - Sayed S., Bakry R.,1 El-Shazly M., El-Oteify M., Terzaki S., Fekry M., EFFECT OF MAJOR BURNS ON EARLY AND LATE ACTIVATING MARKERS OF PERIPHERAL BLOOD T LYMPHOCYTES, Annals of Burns and Fire Disasters, vol. XXV - n. 1, PP.17-21, 2012
    32 - دعاء سيد رفعت عبد العال د/ هبة احمد مادلين عادل عبدة, Increased circulating red cell microparticles (RMP) and platelet microparticles (PMP) in immune thrombocytopenic purpura , Accepted for publication in Thrombosis , 2012
    33 - Mohamed A Ahmed1, Sahar A Mohamed2, Douaa Sayed3 , Long-term antalgic effects of repetitive transcranial magnetic stimulation of motor cortex and serum beta-endorphin in patients with phantom pain , Neurological Research , Vol33 No9, 953-958, 2011
    34 - Badr G1, Sayed D, Alhazza IM, Elsayh KI, Ahmed EA, Alwasel SH , T lymphocytes from malnourished infants are short-lived and dysfunctional cells , Immunobiology., 2011
    35 - ايناس احمد حامد نجلاء حسن ابو فدان هبة أحمد عبد الحفيظ دعاء سيد, PARATHORMONE-25 (OH)-VITAMIN D AXIS AND BONE STATUS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS, Pediatric diabetes , 2011
    36 - Douaa Sayed , Nabila F. Amin , Ghada M. Gala, Monocyte-platelet aggregates and platelet micro-particles in patients with post-hepatitic liver cirrhosis, Thrombosis Research, Vol. 125, No. 5, pp. e228–e233, January, 2010
    37 - Rania Bakry, Douaa Sayed, Hanan Galal, and Sanaa Shaker, Platelet Function, Activation and Apoptosis During and After Apheresis, Therapeutic Apheresis and Dialysis, Vol. 14, No. 5, PP. 457–464, 2010
    38 - Douaa Sayed, Rania Bakry, Nahla El-Sharkawy, Asmaa Zahran, and Muhammed R. Khalaf, Flow cytometric platelet cross-matching to predict platelet transfusion in acute leukemia, Journal of Clinical Apheresis, 2010
    39 - Hamed EA, Abu Faddan NH, Adb Elhafeez HA, Sayed D., Parathormone – 25(OH) -Vitamin D axis and Bone Status in Children and Adolescents with Type 1 Diabetes Mellitus., Journal of Accepted in Pediatric Diabetes , October, 2010
    40 - Badr G, Sayed D, Alhazza IM, Elsayh KI, Ahmed EA, Alwasel SH. , T lymphocytes from malnourished infants are short-lived and dysfunctional cells. , journal imbio, 8, 2010
    41 - Bakry R, Sayed D, Galal H, Shaker S, Platelet function, activation and apoptosis during and after apheresis., Journal Therapeutic Apheresis and Dialysis , Vol. 14 - No. 5, pp. 457 - 464, 2010
    42 - D. Sayed, G. Badr, D. Maximous, N. N. H. Mikhail, F. Abu-Tarboush & I. M. Alhazza, HLA-G and its relation to proliferation index in detection and monitoring breast cancer patients, Tissue Antigens , vol. 75 - No. 1, 40 - 47, January, 2010
    43 - Sayed D, Amin NF, Galal GM., Monocyte-platelet aggregates and platelet micro-particles in patients with post-hepatitic liver cirrhosis., Thromb Res., Vol. 125 - No. 5, pp. 228 - 233, January, 2010
    44 - Khalid I. Elsayh, Douaa Sayed, Gamal Badr, Fas-induced apoptosis in malnourished infants [, Pediatric Allergy and Immunology , April, 2010
    45 - Nagla Hassan Abu Faddan, Douaa Sayed*, Nahla Al- Sharkawy, Apoptosis and mitochondrial membrane potential changes of T lymphocytes from children with Down’s syndrome, Egypt J Pediatr Allergy Immunol, 8-1, 35-40., 8, 2010
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    46 - Abeer Elkady, Yasuhito Tanaka, Fuat Kurbanov, Fuminaka Sugauchi, Masaya Sugiyama, Anis Khan, Douaa Sayed, Ghada Moustafa, AbdEl-Rahman AbdEl-Hameed, and Masashi Mizokami, Genetic Variability of Hepatitis C Virus in South Egypt and Its Possible Clinical Implication , Medical Virology, Vol. 81, No. 6, pp. 1015-1023, 2009
    47 - Mona A. Abu El-Makrem , Yehia Z. Mahmoud , Douaa Sayed , Noussa M. Nassef b, Samir S. Abd El-Kader , Madiha Zakhary , Taghreed Ghazaly , Ragaa Matta, The role of platelets CD40 ligand (CD154) in acute coronary syndromes, Thrombosis Research, Vol. 124, No. 6, pp. 683-688, 2009
    48 - Douaa Sayed,Hosny Badrawy,AMany Ali,Sanaa Shaker , Immunophenotyping and immunoglobulin heavy chain gene rearrangement analysis in cerebrospinal fluid of pediatric patients with acute lymphoblastic leukemia. , Leukemia Research, vol. 33 No.5, PP. 655-661, May, 2009
    49 - Abu el-Makrem MA, Mahmoud YZ, Sayed D, Nassef NM, Abd el-Kader SS, Zakhary M, Ghazaly T, Matta R. , The role of platelets CD40 ligand (CD154) in acute coronary syndromes. , Thromb Res. , Vol. 124 - No. 6, pp. 683-688, 8, 2009
    50 - Elkady A, Tanaka Y, Kurbanov F, Sugauchi F, Sugiyama M, Khan A, Sayed D, Moustafa G, Abdel-Hameed AR, Mizokami M. , Genetic variability of hepatitis C virus in South Egypt and its possible clinical implication. , J Med Virol., Vol. 81 - No. 6, pp. 1015-1023, January, 2009
    51 - Douaa Sayed,Madiha M.El-Attar,and Aliaa A.R. Mohamed Hussein , Evaluation of flow cytometric immunophenotyping and DNA analysis for detection of malignant cells in serosal cavity fluids., Diagnostic Cytopathology, vol. 37- No. 7, pp. 498 - 504, 2009
    52 - Douaa M. Sayed M.D.1,*, Madiha M. EL-Attar M.D.2 and Aliaa A. R. Mohamed Hussein M.D., Evaluation of flow cytometric immunophenotyping and DNA analysis for detection of malignant cells in serosal cavity fluids, Diagnostic Cytopathology Volume 37, Issue 7, pages 498–504, July 2009, 2009
    53 - Sayed D, Badrawy H, Ali AM, Shaker S., Immunophenotyping and immunoglobulin heavy chain gene rearrangement analysis in cerebrospinal fluid of pediatric patients with acute lymphoblastic leukemia., leuk Res., 2009
    54 - Badr G. and Sayed D , Human Melanoma Cells Release Soluble and Functional Receptors , THE EGYPTIAN JOURNAL OF IMMUNOLOGY, Vol. 13, No. 2, pp. 23-31, 2006
    55 - Kamel AM, El-Sharkawy N, Mahmoud HK, Khalaf MR, El Haddad A, Fahmy O, El Fattah RA, Sayed D. , Impact of CD34 subsets on engraftment kinetics in allogeneic peripheral blood stem cell transplantation. , Bone Marrow Transplant. , Vol. 35 - No. 2, pp. 129 - 36, 2005

    Supervisions :

    1- Tasneam esmael mohamed hasaan, Giardiasis as acontiung problem and evaluation of anti gardial effect of some herbs, Ph. D., 22 October 2015
    Supervisors : Prof.Dr. Ahmed kamal dyab Prof.Dr. Doaa abdelhafeaz yones Prof>dr.Douaa mohamed sayed
    2- noha gaber sayed, stat3 and bcr abl gene expression chronic myeloid leukaemia and their relationto imatinib therapy, Ph. D., 30 June 2014
    Supervisors : muhammed raafat khalaf; douaa mohamed sayed; hosny badrawy hamed
    3- Mohamed Ahmed Yehya Abdel-Malek, Targeting Protein Degradation Pathway for Therapeutic Benifits in Multiple Myeloma, Ph. D., 30 December 2016
    Supervisors : Prof. Dr. Nabila Mohamed Thabet Professor of Clinical Pathology, Faculty of Medicine - Assiut University Prof. Dr. Hanan Galal Abdel-Azeem Professor of Clinical Pathology, Faculty of Medicine - Assiut University Prof. Dr. Douaa Mohamed Sayed Professo
    4- Randa Adam, Preparation and Characterization of Silica nanoparticles loaded antioxidants to fight breast cancer, M. Sc, 26 December 2016
    Supervisors : Prof. Dr. Nagwa Abo-Elmaali Prof. Dr. Gamal Abdel-Wahab Prof. Dr. Gamal Badr Prof. Dr. Douaa Sayed

    Awards and Grants :

    1 - " The State Encouragement Prize " in Medical Sciences, 2011.
    2 - " " , 2013.
    3 - " Award for the best research in Oncology field " , 2009.
    4 - " Award for international publication of the year 2009 from South Egypt Cancer " , 2010.
    5 - " award for international publication of the year 2010 from South Egypt Cancer " , 2011.
    Number of courses0 course