Background and aim: Environmental stressors, such as heavy metal pollution, can have devastating effects on biological organisms, leading to conditions like liver toxicity. This study explored the therapeutic potential of a novel iron-based metal-organic framework (Fe-MOF) in mitigating cobalt chloride-induced liver toxicity in rats. Methods: Utilizing a solvothermal synthesis method, CWP/MOF was created and characterized using X-ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy. Adult male rats were divided into four groups, each consisting of six rats. The groups were treated as follows: Group 1 (Control): Received 0.5 mL/day of distilled water only. Group 2 (CoCl₂): Treated with cobalt chloride (100 mg/kg/day) dissolved in distilled water. Group 3 (CoCl₂ + Fe-MOFs): Treated with cobalt chloride (100 mg/kg/day) and FeMOFs dissolved in distilled water. Group 4 (CoCl₂ + CWP/MOF): Treated with cobalt chloride (100 mg/kg/day) and CWP/MOF, dissolved in distilled water. All groups received treatment for a duration of two months. Results: there was a one-dimensional structure and multienzyme-like activity. CWP/MOF prevented apoptosis and reduced the histopathological effect and collagen fiber percentage caused by cobalt chloride in the liver. Nanotechnology was used to increase the therapeutic efficiency of camel whey protein against the harmful effects associated with environmental stress-induced liver toxicity by cobalt chloride in rats. Conclusions: This study highlights the potential of CWP/MOF as a groundbreaking therapeutic agent for induced liver toxicity, with promising applications in regenerative medicine and tissue engineering. By harnessing the unique properties of CWP/MOF, researchers may uncover new avenues for treating liver-related disorders and promoting overall health.