Skip to main content

Reproductive and endocrine-disrupting toxicity of pyrogallol in catfish (Clarias gariepinus)

Research Authors
Mohamed Hamed, Rashad EM Said, Christopher J Martyniuk, Hamdy AM Soliman, Alaa El-Din H Sayed, Alaa GM Osman
Research Abstract

Endocrine disruptors are synthetic or natural chemicals that can agonize/antagonize hormone receptors or can interfere with the production and secretion of hormones, leading to altered tissue histology and physiology. Pyrogallol is a contaminant widely distributed in aquatic environments that presents health risks to both humans and animals. However, the potential for endocrine disruption by pyrogallol, particularly in fish, are lacking. The purpose of this study was to shed light on how pyrogallol may affect hormone signalling, histopathology, and reproductive outcomes in African catfish Clarias gariepinus. To investigate this, African catfish were exposed to one sublethal concentration of pyrogallol at either 0, 1, 5 or 10 mg/L for 15 days. We then assessed the effects of pyrogallol on the thyroid gland as well as the reproductive system by measuring sex hormone, seminal quality, gonadal histopathology, and …

Research Date
Research Department
Research Journal
Environmental Pollution
Research Member
Research Year
2024