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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
221 A highly sensitive enzyme immunoassay for evaluation of 2_-deoxycytidine plasma level as a prognostic marker for breast cancer chemotherapy 2009
222 Evaluation of The Pharmacokinetic of New Amantadine Prodrugs As Hepatic Delivery Systems to Enhance Its Activity Against HCV by A New HPLC Method. 2009
223 Quantitative Structure-Activity Relationship (QSAR) Studies
on a Series of 1,3,4-thiadiazole-2-thione Derivatives as
Tumor-Associated Carbonic Anhydrase IX Inhibitors
2009
224 Design, Synthesis and Molecular Modeling Study of
Acylated 1,2,4-Triazole-3-Acetates with Potential Anti-
Inflammatory Activity
2009
225 Preparation, Antimicrobial and Estrogenic Activity of Ferutinin and Selected Analogs. 2009
226 Quantitative Structure-Activity Relationship (QSAR) Studies
on a Series of 1,3,4-thiadiazole-2-thione Derivatives as
Tumor-Associated Carbonic Anhydrase IX Inhibitors
2009
227 Synthesis and Investigation of Anti-Inflamma-tory Activity
and Gastric Ulcerogenicity of Novel Nitric Oxide-Donating
Pyrazoline Derivatives
2009
228 Chlorzoxazone Esters of some Non-Steroidal Anti-
Inflammatory (NSAI) Carboxylic Acids as Mutual Prodrugs:
Design, Synthesis, Pharma-cological Investigations and
Docking Studies
2009
229 Synthesis and Investigation of Anti-Inflamma-tory Activity
and Gastric Ulcerogenicity of Novel Nitric Oxide-Donating
Pyrazoline Derivatives
2009
230 THE PROTEOLYTIC STABILITY AND CYTOTOXICITY STUDIES OF L-ASPARTIC AND L-DIAMINOPROPIONIC ACID DERIVED OLIGOMERS 2009