Hydroxy Vasntine, A New Pyrroloquinazoline Alkaloids Trisulcus (Forssk) Nees

Faculty of Pharmacy

Assiut University

Hydroxy Vasntine, A New Pyrroloquinazoline Alkaloids Trisulcus (Forssk) Nees

Research Authors
Mohamed A. El-Shanawany, Hanaa M. Sayed, Sabrin R. M. Ibrahim, Marwa A. A. Fayed
Research Department
Department of Pharmacognosy
Research Journal
J. Nat. Prod. Plant Resour
Research Rank
1
Research Vol
Vol. 1,No. 4
Research Year
2011
Research Member
Sabrin Ragab Mohamed Ibrahim
Research Abstract

Hydroxy vasntine (1), a new pyrroloquinazoline alkaloidsalong with two known compounds: 7-hydroxy vasicine (2) and 7-hydroxy vasicine (3) were isolated from the aerial parts of Anisotes trisulcus (Forssk) Nees (Acanthaceae). Their structures were established by UV, IR, ID NMR, in addition to mass spectroscopic data and comparison with literature data. The different fractions were evaluated for their cytotoxic activity using the brine shrimp bioassay.