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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
361 Paracetamol (Acetaminophen) Esters of Some Non-steroidal Anti-inflammatory Carboxylic acids Drugs as Mutual Prodrugs with Improved Therapeutic Index. 1998
362 Metronidazle Twin Esters Prodrugs II : Non Identical Twin Esters of Metronidazole and Some Antiprotozoal Halogenated Hydroxyquinoline Derivatives. 1998
363 Paracetamol (Acetaminophen) Esters of Some Non-steroidal Anti-inflammatory Carboxylic acids Drugs as Mutual Prodrugs with Improved Therapeutic Index. 1998
364 Esters Twin Drugs of Metronidazole : Synthesis, Physicochemical properties, Kinetic studies and Antigardial activity. 1998
365 Chitosan Conjugates of Ibuprofen and Flurbiprofen: Synthesis, Characterization and in vitro Stability. 1998
366 Potent Anticonvulsant Paeonimetabolin-I Derivatives Obtained by Incubation of Paeoniflorin and Sulfhydryl Compounds With Lactobacillus Brevis. 1998
367 Esters Twin Drugs of Metronidazole : Synthesis, Physicochemical properties, Kinetic studies and Antigardial activity. 1998
368 Chitosan Conjugates of Ibuprofen and Flurbiprofen: Synthesis, Characterization and in vitro Stability. 1998
369 Polymeric prodrug:  and -poly (N-hydroxy-ethyl) aspartamide as carrier for controlling the release of theophylline. 1998
370 Potent Anticonvulsant Paeonimetabolin-I Derivatives Obtained by Incubation of Paeoniflorin and Sulfhydryl Compounds With Lactobacillus Brevis. 1998