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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
301 1,2-Dihydroisoquinoline-N-Acetic Acid Derivatives as New Carriers for Specific Brain Delivery I : Synthesis and Estimation of Oxidation Kinetics Using Multivariate Calibration Method. 2003
302 1,2-Dihydroisoquinoline-N-Acetic Acid Derivatives as New Carriers for Specific Brain Delivery I : Synthesis and Estimation of Oxidation Kinetics Using Multivariate Calibration Method. 2003
303 Synthesis and Antitubercular Activity of some Schiff Bases Derived from Mannich Bases of Isatin and Isonicotinic Acid Hydrazide (INH). 2003
304 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug. 2003
305 2Unusual “Senseless” 2’-5’ Oligoribonucleotide with a Potent Anti-HIV Activity. 2003
306 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug. 2003
307 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug. 2003
308 1,2-Dihydroisoquinoline Derivatives as New Carrier for Brain Specific Delivery. 2002
309 HIV PROTEASE INIHIBITORS: PEPTIDOMIMETIC DRUGS AND FUTURE
PERSPECTIVES
2002
310 Synthesis, Degradation kinetics and In-vitro Antimicrobial Activity of Tetrahydro-2H-1,3,5- thiadiazine-2-thione Derivatives of Some b-Amino Acids. 2002