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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
91 Schiff Bases of Indoline-2,3-dione (Isatin) Derivatives as Efficient Agents Against Resistant Strains of Mycobacterium tuberculosis 2015
92 Annonaceous Acetogenins as a new anticancer agent
2015
93 Cu (I) Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition (CuAAC): Synthesis of 17α-[1-(Substituted Phenyl)-1,2,3-Triazol-4-yl]-19-Nortestosterone-17β-yl Acetates Targeting Progestational and Antipro-Liferative Activities 2015
94 Lipases-catalyzed enantioselective kinetic resolution of alcohols 2015
95 Cu (I) Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition (CuAAC): Synthesis of 17α-[1-(Substituted Phenyl)-1,2,3-Triazol-4-yl]-19-Nortestosterone-17β-yl Acetates Targeting Progestational and Antipro-Liferative Activities 2015
96 Lipases-catalyzed enantioselective kinetic resolution of alcohols 2015
97 Synthesis, anti-inflammatory and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetone thiosemicarbazone cyclized derivatives as PLA-2 inhibitors 2015
98 Cu (I) Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition (CuAAC): Synthesis of 17α-[1-(Substituted Phenyl)-1,2,3-Triazol-4-yl]-19-Nortestosterone-17β-yl Acetates Targeting Progestational and Antipro-Liferative Activities 2015
99 Lipases-catalyzed enantioselective kinetic resolution of alcohols 2015
100 Optogenetic Inhibitor of the Transcription Factor CREB 2015