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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
191 Chlorzoxazone Esters of some Non-Steroidal Anti-
Inflammatory (NSAI) Carboxylic Acids as Mutual Prodrugs:
Design, Synthesis, Pharma-cological Investigations and
Docking Studies
2009
192 Antimicrobial and Estrogenic Activity of Ferutinin and Selected Semi-Synthetic Analogs. 2009
193 1-Malonyl-1,4-dihydropyridine as a Novel Carrier for
Specific Delivery of Drugs to the Brain
2009
194 Small-Sized Human Immunodeficiency Virus Type-1
Protease Inhibitors Containing Allophenylnorstatine to
Explore the S2' Pocket
2009
195 Chlorzoxazone Esters of some Non-Steroidal Anti-
Inflammatory (NSAI) Carboxylic Acids as Mutual Prodrugs:
Design, Synthesis, Pharma-cological Investigations and
Docking Studies
2009
196 Evaluation of The Pharmacokinetic of New Amantadine Prodrugs As Hepatic Delivery Systems to Enhance Its Activity Against HCV by A New HPLC Method. 2009
197 1-Malonyl-1,4-dihydropyridine as a Novel Carrier for
Specific Delivery of Drugs to the Brain
2009
198 Design, synthesis and molecular modeling study of 1,2,4-triazole carbohydrazide derivatives with potential antimicrobial and anti-inflammatory activities.

2009
199 Synthesis of Some Pyrazolylbenzenesulfon-amide
Derivatives as Anti-Inflammatory Antimicrobial Agents
2009
200 Preparation, Antimicrobial and Estrogenic Activity of Ferutinin and Selected Analogs. 2009