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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
291 Optical Isomers of 3-substituted-5-(2-carboxyethyl)-1,3,5- thiadiazin-2-thiones of Potential Antimicrobial Activity, Synthesis, and Solid State Stability. 2004
292 Synthesis and antimicrobial activity of certain nitropyridine derivatives 2004
293 Synthesis and antibacterial screening of some 2,5,7-triaryl-1,2,4-triazolo[1,5-a]pyrimidines
2004
294 1,2-Dihydroisoquinoline-N-Acetic Acid Derivatives as New Carriers for Specific Brain Delivery I : Synthesis and Estimation of Oxidation Kinetics Using Multivariate Calibration Method. 2003
295 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug. 2003
296 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug. 2003
297 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug. 2003
298 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug. 2003
299 Synthesis and Antitubercular Activity of some Schiff Bases Derived from Mannich Bases of Isatin and Isonicotinic Acid Hydrazide (INH). 2003
300 Brain delivery of HIV protease inhibitors 2003