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Stationary‐Angle Conditions and Bertrand Offsets in Timelike‐Ruled Surfaces

Research Abstract

In thisstudy,weintroducetheconceptofstationary-angletimelike-ruledsurfacesandexaminetheirgeometricproperties,
particularly inrelationtotheirBertrandoffsets.Atimelike-ruledsurfaceisgeneratedbythemotionofastraightrulingalonga
striction curve,anditsstructureisanalyzedusingtheBlaschkeandDarbouxframes.Wederivekeygeometricinvariants,including
spherical curvature,geodesiccurvature,normalcurvature,andgeodesictorsion.Additionally,weestablishtheconditionsunder
which thestrictioncurveofatimelike-ruledsurfacebehavesasageodesic,anasymptoticcurve,oracurvatureline.Specialcases,
such astimelike-tangentialdevelopablesandtimelike-cones,arealsodiscussed.Usingcurvature-axisanalysis,wedevelopahigher-
order contactframeworktobetterunderstandthebehaviorofthesesurfaces.Finally,weinvestigatetheBertrandoffsetsof
stationary-angle timelike-ruledsurfaces,provingthattheypreserveastationaryanglebetweentheirrulingsanddetermining
the necessaryconditionsfortheirexistence.ThisworkenhancestheunderstandingofdifferentialgeometryinLorentzianspaces
and providesnewinsightsintoruledsurfacesinMinkowskispace.

Research Authors
Rashad A. Abdel-Baky
Research Date
Research Department
Research Journal
Advances in Mathematical Physics
Research Year
2025

Fixed-axis spacelike ruled surfaces and their evolute offsets

Research Abstract

This study investigates fixed-axis spacelike ruled surfaces and their evolute offset counterparts
within E31
(Minkowski 3-space). The analysis utilizes the Blaschke frame associated
with the striction curves of these surfaces. Spacelike ruled surfaces play a crucial
role in various fields of both classical and modern physics. The research begins by introducing
the fundamental concepts of fixed-axis spacelike ruled surfaces and defining a
height function that establishes the necessary criteria for a ruled surface to be classified
as a fixed-axis spacelike ruled surface. Subsequently, the study derives parameterization
for both the fixed-axis spacelike ruled surfaces and their evolute offsets. Finally, several
surface models are extended and visually represented through graphical illustrations.

Research Authors
Rashad A. Abdel-Baky
Research Date
Research Department
Research Journal
PLoS One
Research Year
2025

Space like surface families interpolating common asymptotic curves in Minkowski 3-space

Research Abstract

In this paper, we propose a method for constructing families of spacelike
surfaces in Minkowski 3-space 𝔼31
that share Bertrand curves as asymptotic
curves. By using marching-scale functions, we derive the necessary conditions,
provide flexible formulations, and establish a framework for constructing mutual
spacelike Bertrand curves. Examples show how different functions generate
surfaces interpolating the common asymptotic curves, offering new insights for
geometric modeling and ruled surface theory.

Research Authors
Rashad A. Abdel-Baky
Research Date
Research Department
Research Journal
Frontiers in Physics
Research Year
2025

Quasi-normal developable surfaces and their singularities in Euclidean 3-Space

Research Abstract

The developable surface (DS) is a curved surface that can be spread out on a plane without stretching or tearing, which is
widely operated in much fields of engineering and industrialization. This research displays a new approach of producing developable
surfaces in E3(Euclidean 3-space). At first, we start a modified frame over a curve, named as the quasi-frame. We then initiate an
exemplification of a DS and call it a quasi-normal DS. At the essence of this work, we examine the existence and uniqueness of such
DS, then consider its categorizations via singularity theory and unfolding theory (UT). Finally, two paradigms related to our approach
are presented for the purpose of clarity.

Research Authors
Rashad A. Abdel-Baky
Research Date
Research Department
Research File
paper 2.pdf (455.98 KB)
Research Journal
Appl. Math. Inf. Sci.
Research Year
2025

On the kinematic-geometry of a line congruence

Research Abstract

This study examines the kinematic geometry of line congruences in Euclidean 3-space
E3, defined as two-parameter families of lines determined by a director surface and unit
direction vectors. The fundamental properties of ruled surfaces within a line congruence
are analyzed, with particular focus on their developability conditions and classification
into torsal and non-torsal surfaces. The dual unit sphere representation is introduced,
along with the fundamental forms of line congruences, leading to the derivation of mean
and Gaussian curvature parameters. Additionally, the study explores the relationships
between principal ruled surfaces and their curvature properties within the kinematic
framework. Furthermore, Hamilton and Mannheim formulae are derived, offering deeper
insights into the differential geometry and motion of line congruences.

Research Authors
Rashad A. Abdel-Baky
Research Date
Research Department
Research File
paper 1.pdf (851.79 KB)
Research Journal
International Journal of Geometric Methods in Modern Physics
Research Year
2025

Mycosynthesis of silver nanoparticles by Aspergillus templicola OR480102: a multifaceted approach for antibacterial, anticancer, and scratch assay applications

Research Abstract

Background Regarding their distinct physico-chemical and bioactivity characteristics, silver nanoparticles ‘AgNPs’ are
extensively utilized in numerous scientifc purposes.
Results Within this current investigation, for the frst time, we evaluated how the extracellular extract of the
isolate MAK223 generated exceptionally fxed AgNPs. The isolate was genetically identifed as Aspergillus templicola
OR480102. The generated AgNPs’ physico-chemical characteristics were assessed using ultraviolet-vis spectroscopy,
transmission electron microscopy (TEM), and Fourier transform infrared spectrometry (FT-IR). The maximum
absorption in the UV-vis spectrum was obtained at 420 nm, matching the silver nanoparticles’ surface plasmon
absorbance. A. templicola OR480102 produced uniformly dispersed AgNPs between 5 and 25 nm with a mean
dimension of 17.78537 ± 1.36 nm using TEM. FT-IR analysis identifed functional groups (e.g., -OH, C = O) in the
fungal fltrate that mediate AgNP synthesis and capping. To verify AgNPs stability, the dynamic light scattering
(DLS) approach is employed. Optimal conditions for AgNPs synthesis were 10 days of incubation, one mM silver
nitrate concentration, pH 11, and elevated temperatures. AgNPs demonstrated efcacy against clinically relevant
pathogens: S. typhimurium ‘ATCC 14028’, B. subtilis ‘ATCC 6633’, S. aureus ‘ATCC 25923’, and E. coli ‘ATCC 29213’ were
used in the study. Also, using AgNPs derived from the fltrate of A. templicola OR480102 shows signifcant potential
as a novel therapeutic approach against breast cancer cells ‘MCF-7’. The scratch assay of ‘MCF-7’ cells demonstrates
the suppressive impact of AgNPs for these cell lines during proliferation by promoting apoptosis and reducing cell
migration.
Conclusion Based on physico-chemical characteristics of AgNPs’ and their antimicrobial and anticancer activities,
it cleared that the selected strain Aspergillus templicola OR480102 is a promising producer of stable AgNPs’ with
signifcant bioactivities which could be applicable in different felds. 
 

Research Authors
Marwa M. Abdel-Kareem, Maysa M. A. Ali, Abd El-Latif Hesham, Hossam E. F. AbdelRaheam and Marwa Obiedallah.
Research Date
Research File
Research Journal
BMC Biotechnolgy
Research Member
Research Pages
18
Research Publisher
BMC
Research Vol
25
Research Year
2025

ANALYSIS OF AEROMAGNETIC DATA FOR LOCATING POTENTIAL GEOTHERMAL RESOURCES IN NORTHERN WESTERN DESERT OF EGYPT

Research Abstract

Geothermal resources in Egypt are useful as a promising source of renewable energy. Little attempts have been carried out to expansively investigate the geothermal potentiality in the Western Desert. The present study is focused on the investigation of geothermal resources in the Northern Western Desert. To achieve this objective, the available aeromagnetic data is firstly reduced to the pole (RTP), then filtered using tilt derivative (TDR) and Butterworth low and high pass methods. The major trends of the different predominant detected local and regional lineaments (probably basement structures) have been determined and correlated with surface structures. To delineate the basement depth configuration, power spectral analysis of aeromagnetic data, as well as constructing 2D modeling (verified by drilled wells data) were applied. The results have been used to estimate the Curie point depth (CPD), geothermal 

Research Authors
GM Abdelaleem, GZ Abdelaal, AA Omran, AA Abdel-Halim, HS Mohamed
Research Date
Research Department
Research Journal
Russian Geology and Geophysics
Research Year
2025

Magmatic–Hydrothermal Transition of Granitic System: Evidence from Mineral Reaction Overprints in the Homrit Waggat Granite Intrusion (Central Eastern Desert, Egypt)

Research Abstract

The Precambrian Homrit–Waggat granite is a post‐orogenic batholithic intrusion located in the northern region of the Nubian Shield, characterized by a typical annular morphology and significant secondary alteration. This study aims to elucidate the processes that have shaped the intrusion in both macroscopic and microscopic perspectives, employing a combination of field observation and petrographic analysis alongside major and trace element compositions of minerals. Within the central region of the pluton, biotite and amphibole are observed sporadically, while the predominant crystallization of anhydrous oligoclase in the outer regions has led to a progressive increase in volatile components within the residual melt, ultimately resulting in a volatile‐saturated aluminosilicate melt. The exsolved fluids subsequently interacted with the previously crystallized mineral assemblage, producing metasomatic 

Research Authors
Yujie SUN, Hassan ABBAS, Mohamed A ABU EL-RUS, Ali A KHUDEIR, Julie AS MICHAUD, Sadiq HAMID, Simon GOLDMANN, Khairya FAWZY, Chao ZHANG
Research Date
Research Department
Research Journal
Acta Geologica Sinica (English Edition)
Research Year
2025

Aeromagnetic analysis of the post-collisional Homrit Waggat ring pluton, Southeastern Desert, Egypt: evidence for cauldron subsidence in a mid-crustal magma chamber

Research Abstract

The post-collisional Homrit Waggat ring pluton exposed in southeastern Egypt preserves a record of events in the magma plumbing system at mid-crustal depths (c. 11 km). The pluton consists of two successive granite rings: an inner syeno-granite ring (c. 630–626 Ma) and an outer alkali granite ring (c. 635 Ma). High-resolution aeromagnetic data for the total magnetic intensity were used to construct vertical cross-sections through the pluton to configure its subsurface geometry and internal structure. A reduction-to-pole filter was applied to the total magnetic intensity data to position the magnetic anomalies directly above their sources. Several derivation techniques were applied to the reduction-to-pole data, including the tilt derivation filter to highlight the subsurface structural contacts and faults, the analytical signal technique to delineate the concentric magnetic rings, and both 3D Euler deconvolution and 2D

Research Authors
Haby S Mohamed, Chao Zhang, Ali A Khudeir, Francois Holtz, Sadeq H Seif, Mohamed A Abu El-Rus
Research Date
Research Department
Research Journal
Journal of the Geological Society
Research Year
2026

Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma

Research Abstract


Highlights

LGMN is specifically expressed in TAMs and regulated by HIF1α
LGMN promotes TAM immunosuppressive polarization via the GSK-3β-STAT3 pathway
Inhibition of macrophage HIF1α and LGMN impairs GBM progression
Blockade of the HIF1a-LGMN axis synergizes with anti-PD1 therapy in GBM

Summary

Glioblastoma (GBM) is a hypoxic and “immune-cold” tumor containing rich stromal signaling molecules and cell populations, such as proteases and immunosuppressive tumor-associated macrophages (TAMs). Here, we seek to profile and characterize the potential proteases that may contribute to GBM immunosuppression. Legumain (LGMN) emerges as the key protease that is highly enriched in TAMs and transcriptionally upregulated by hypoxia-inducible factor 1-alpha (HIF1α). Functionally, the increased LGMN promotes TAM immunosuppressive polarization via activating the GSK-3β-STAT3 signaling pathway. Inhibition of macrophage HIF1α and LGMN reduces TAM immunosuppressive polarization, impairs tumor progression, enhances CD8+ T cell-mediated anti-tumor immunity, and synergizes with anti-PD1 therapy in GBM mouse models. Thus, LGMN is a key molecular switch connecting two GBM hallmarks of hypoxia and immunosuppression, providing an actionable therapeutic intervention for this deadly disease.
 


 

Research Authors
Lizhi Pang,Songlin Guo,Fatima Khan, Madeline Dunterman,Heba Ali, Yang Liu, Yuyun Huang, and Peiwen Chen
Research Date
Research Department
Research Journal
Cell Report Medicine
Research Member
Research Year
2023
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