Do Osteobiologics Augment Fusion in Anterior Cervical Discectomy and Fusion Surgery Performed With Mechanical Interbody Devices (Polyether ether ketone, Carbon Fiber, Metal …

Faculty of Medicine

Assiut University

Do Osteobiologics Augment Fusion in Anterior Cervical Discectomy and Fusion Surgery Performed With Mechanical Interbody Devices (Polyether ether ketone, Carbon Fiber, Metal …

Research Authors
Viswanadha Arun-Kumar, Stipe Corluka, Zorica Buser, Yabin Wu, Mohammad El-Sharkawi, Charles André Carazzo, Nikhil Ponugoti, Jeffrey C Wang, Hans Jörg Meisel, AO Spine Knowledge Forum Degenerative
Research Date
Research Department
Department of Orthopedic Surgery and Traumatology
Research Journal
Global Spine Journal
Research Member
Mohammad Mostafa Mohammad El-Sharkawi
Research Publisher
SAGE Publications
Research Website
https://journals.sagepub.com/doi/full/10.1177/21925682231188626
Research Year
2024
Research_Pages
24-33
Research Abstract

Study design

Systematic Review of the Literature.

Objective

The purpose of this study was to perform a systematic review describing fusion rates for anterior cervical discectomy and fusion (ACDF) using autograft vs various interbody devices augmented with different osteobiologic materials.

Methods

A systematic review limited to the English language was performed in Medline, Embase and Cochrane library using Medical Subject Heading (MeSH) terms. Studies that evaluated fusion after ACDF using autografts and osteobiologics combined with PEEK, carbon fibre, or metal cages were searched for. Articles in full text that met the criteria were included in the review. The main outcomes evaluated were the time taken to merge, the definition of the fusion assessment, and the modality of the fusion assessment. The risk of bias of each article was assessed by the MINORS score or ROB 2.0 depending on the randomisation …