الابحاث الخاصة بالقسم

كلية الصيدلة

جامعة أسيوط

قسم الكيمياء العضوية الصيدلية

 

# العنوان سنة البحث
61 Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities 2022
62 Discovery of new pyrimido[5,4-c]quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies 2022
63 New pyrimidine/thiazole hybrids endowed with analgesic, anti-inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX-2/sEH dual inhibition 2022
64 Crystal structure and Hirshfeld surface analysis of 5-acetyl-3-amino-6-methyl- N -phenyl-4-[( E )-2-phenylethenyl]thieno[2,3- b ]pyridine-2-carboxamide 2022
65 New 1, 3, 4‐oxadiazoles linked with the 1, 2, 3‐triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase 2022
66 New 1,3,4-Oxadiazole-Chalcone/Benzimidazole Hybrids as Potent Anti-proliferative Agents 2022
67 The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45 −/− immunodeficient B cells 2022
68 Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties 2022
69 Novel piperine-carboximidamide hybrids: design, synthesis, and antiproliferative activity via a multi-targeted inhibitory pathway 2022
70 Design, synthesis, and modelling study of new 1,2,3- triazole/chalcone hybrids with antiproliferative action as epidermal growth factor receptor inhibitors 2022