الابحاث الخاصة بالقسم

كلية الصيدلة

جامعة أسيوط

قسم الكيمياء العضوية الصيدلية

 

# العنوان سنة البحث
1 Fatty Acid Conjugated Chalcones as Tubulin Polymerization Inhibitors: Design, Synthesis, QSAR, and Apoptotic and Antiproliferative Activity 26/4/2023
2 N-substituted-5-[(2,5-dihydroxybenzyl)amino]salicylamides as lavendustin analogs: antiproliferative activity, COMPARE analyses, mechanistic, docking, ADMET and toxicity studies 2025
3 Tetrahydrocarbazoles incorporating 5-arylidene-4-thiazolinones as potential antileukemia and antilymphoma targeting tyrosine kinase and tubulin polymerase enzymes: Design, synthesis, structural, biological and molecular docking studies 2024
4 New diaryl-1,2,4-triazolo[3,4-a]pyrimidine hybrids as selective COX-2/sEH dual inhibitors with potent analgesic/anti-inflammatory and cardioprotective properties 2024
5 Design, synthesis, and antiproliferative activity of new 1, 2, 3-triazole/quinazoline-4-one hybrids as dual EGFR/BRAF V600E inhibitors 2024
6 Design and synthesis new dihydropyrimidine derivatives with cytotoxic effect as dual EGFR/VEGFR-2 inhibitors 2024
7 Design and synthesis of new 1, 2, 4-oxadiazole/quinazoline-4-one hybrids with antiproliferative activity as multitargeted inhibitors 2024
8 Convenient synthesis and X-ray determination of 2-amino-6H-1,3,4-thiadiazin-3-ium bromides endowed with antiproliferative activity 2024
9 Bioassay-guided isolation and in Silico characterization of cytotoxic compounds from Hemimycale sp. Sponge targeting A549 lung cancer cells 2024
10 Synthesis new series of 4-pyrazolylquinolinones with apoptotic antiproliferative effects as dual EGFR/BRAFV600E inhibitors 2024