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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
221 Fluorinated 1,2,4-Triazolo[1,5-a]Pyrimidine-6-Carboxylic
Acid Derivatives as Antimyco-bacterial Agents
2009
222 Biotransformation Studies of Prednisone Using
Human Intestinal Bacteria. Part II: Anaerobic
Incubation and Docking Studies
2009
223 Solution-Phase Synthesis of Small Schiff Bases Combinatorial Library with Potential Antitubercular Activity 2009
224 Quantitative Structure-Activity Relationship (QSAR) Studies
on a Series of 1,3,4-thiadiazole-2-thione Derivatives as
Tumor-Associated Carbonic Anhydrase IX Inhibitors
2009
225 Design, Synthesis and Molecular Modeling Study of
Acylated 1,2,4-Triazole-3-Acetates with Potential Anti-
Inflammatory Activity
2009
226 Biotransformation Studies of Prednisone Using
Human Intestinal Bacteria. Part II: Anaerobic
Incubation and Docking Studies
2009
227 Selective Spectrophotometric and Fluorometric Method for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with Sodium 1,2- Naphthoquinone-4-Sulphonate 2009
228 Quantitative Structure-Activity Relationship (QSAR) Studies
on a Series of 1,3,4-thiadiazole-2-thione Derivatives as
Tumor-Associated Carbonic Anhydrase IX Inhibitors
2009
229 Design, Synthesis and Molecular Modeling Study of
Acylated 1,2,4-Triazole-3-Acetates with Potential Anti-
Inflammatory Activity
2009
230 The Proteolytic Stability and Cytotoxicity Studies of l‐Aspartic Acid and l‐Diaminopropionic Acid derived β‐Peptides and a Mixed α/β‐Peptide 2009