Department Researches & Publications

Faculty of Pharmacy

Assiut University

Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
141 Design and Synthesis of 17α-(1-Substituted-1,2,3–Triazol-4-yl)-19-Nortestosterone Acetate Derivatives Using Click Chemistry.
 		2012
142 Pharmacokinetic and Ulcerogenic Studies of Naproxen Prodrugs Designed for Specific Brain Delivery 2012
143 Design and Synthesis of 17α-(1-Substituted-1,2,3–Triazol-4-yl)-19-Nortestosterone Acetate Derivatives Using Click Chemistry.
 		2012
144 NGR peptide ligands for targeting CD13/APN identified through peptide array screening resemble fibronectin sequences 2012
145 Minor Structural Modifications to Alchemix Influence Mechanism of Action and Pharmacological Activity 2012
146 Schiff Bases of Indoline-2,3-Dione (Isatin) with Potential Antiproliferative Activity 2012
147 Design and Synthesis of 17α-(1-Substituted-1,2,3–Triazol-4-yl)-19-Nortestosterone Acetate Derivatives Using Click Chemistry.
 		2012
148 Novel Schiff Bases of Indoline-2,3-Dione and Nalidixic Acid Hydrazide: Synthesis, In Vitro Antimycobacterial and In Silico Mycobacterium Tuberculosis (Mtb) DNA Gyrase Inhibitory Activity 2012
149 Design and Synthesis of 17α-(1-Substituted-1,2,3–Triazol-4-yl)-19-Nortestosterone Acetate Derivatives Using Click Chemistry.
 		2012
150 (Z)-Ethyl 2-cyano-2-{2-[5,6-dimethyl-4-(thiophen-2-yl)-1H-pyrazolo[3,4-b]-pyridin-3-yl]-hydrazinylidene}acetate 2011