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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
251 Novel beta-peptides from L-aspartic acid and beta-amino-4-alanine: Solution conformation and stability studies 2007
252 Design, Synthesis and Antitubercular Evaluation of Small Schiff Base Combinatorial Library. 2007
253 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
254 Design, Synthesis and Antitubercular Evaluation of Small Schiff Base Combinatorial Library. 2007
255 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
256 Pre- and post-initiation chemoprevention activity of 2-alkyl/aryl selenazolidine-4(R)-carboxylic acids against tobacco-derived nitrosamine (NNK)-induced lung tumors in the A/J mouse

2007
257 Design, Synthesis and Antitubercular Evaluation of Small Schiff Base Combinatorial Library. 2007
258 Sensitivity of Escherichia coli to L-selenaproline and other L-proline analogues in laboratory culture media and normal. human urine Charles Deutch. 2006
259 Novel 1,2,4-triazole-3-mercaptoacetic acid derivatives as potential antimycobacterial and antimicrobial agents
2006
260 Acute Effects of Novel Selenazolidines on Murine Chemoprotective Enzymes. 2006