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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
211 The trichloroethyl group as a protecting group for sulfonates and its application to the synthesis of a disulfonate analog of the tyrosine sulfated PSGL-1143−50 peptide 2009
212 Chlorzoxazone Esters of some Non-Steroidal Anti-
Inflammatory (NSAI) Carboxylic Acids as Mutual Prodrugs:
Design, Synthesis, Pharma-cological Investigations and
Docking Studies
2009
213 Synthesis and Investigation of Anti-Inflamma-tory Activity
and Gastric Ulcerogenicity of Novel Nitric Oxide-Donating
Pyrazoline Derivatives
2009
214 Efficient Solid Phase Synthesis of Sulfotyrosine Peptides using a Sulfate Protecting Group Strategy 2009
215 THE PROTEOLYTIC STABILITY AND CYTOTOXICITY STUDIES OF L-ASPARTIC AND L-DIAMINOPROPIONIC ACID DERIVED OLIGOMERS 2009
216 Chlorzoxazone Esters of some Non-Steroidal Anti-
Inflammatory (NSAI) Carboxylic Acids as Mutual Prodrugs:
Design, Synthesis, Pharma-cological Investigations and
Docking Studies
2009
217 1-Malonyl-1,4-dihydropyridine as a Novel Carrier for
Specific Delivery of Drugs to the Brain
2009
218 Small-Sized Human Immunodeficiency Virus Type-1
Protease Inhibitors Containing Allophenylnorstatine to
Explore the S2' Pocket
2009
219 Antimicrobial and Estrogenic Activity of Ferutinin and Selected Semi-Synthetic Analogs. 2009
220 Chlorzoxazone Esters of some Non-Steroidal Anti-
Inflammatory (NSAI) Carboxylic Acids as Mutual Prodrugs:
Design, Synthesis, Pharma-cological Investigations and
Docking Studies
2009