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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
251 Design, Synthesis and Antitubercular Evaluation of Small Schiff Base Combinatorial Library. 2007
252 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
253 Design, Synthesis and Antitubercular Evaluation of Small Schiff Base Combinatorial Library. 2007
254 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
255 Pre- and post-initiation chemoprevention activity of 2-alkyl/aryl selenazolidine-4(R)-carboxylic acids against tobacco-derived nitrosamine (NNK)-induced lung tumors in the A/J mouse

2007
256 Murine Hepatoma (Hepa1c1c7) Cells: A Responsive In Vitro System for Chemoprotective Enzyme Induction by Organoselenium Compounds

2007
257 Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity 2007
258 The Utility and Synthetic Uses of Mannich Reaction: An efficient Route for Synthesis of Thiadiazino-[1,3,5][3,2-a]Benzimidazoles. 2006
259 Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice. 2006
260 Synthesis of 5-Phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic Acid Derivatives of Potential Anti-inflammatory Activity. 2006