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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
211 Selective Spectrophotometric and Fluorometric Method for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with Sodium 1,2- Naphthoquinone-4-Sulphonate 2009
212 Design, synthesis and molecular modeling study of 1,2,4-triazole carbohydrazide derivatives with potential antimicrobial and anti-inflammatory activities.

2009
213 Antimicrobial and Estrogenic Activity of Ferutinin and Selected Semi-Synthetic Analogs. 2009
214 Quantitative Structure-Activity Relationship (QSAR) Studies
on a Series of 1,3,4-thiadiazole-2-thione Derivatives as
Tumor-Associated Carbonic Anhydrase IX Inhibitors
2009
215 Design, Synthesis and Molecular Modeling Study of
Acylated 1,2,4-Triazole-3-Acetates with Potential Anti-
Inflammatory Activity
2009
216 A highly sensitive enzyme immunoassay for evaluation of 2_-deoxycytidine plasma level as a prognostic marker for breast cancer chemotherapy 2009
217 Evaluation of The Pharmacokinetic of New Amantadine Prodrugs As Hepatic Delivery Systems to Enhance Its Activity Against HCV by A New HPLC Method. 2009
218 Design, Synthesis and Molecular Modeling Study of
Acylated 1,2,4-Triazole-3-Acetates with Potential Anti-
Inflammatory Activity
2009
219 Quantitative Structure-Activity Relationship (QSAR) Studies
on a Series of 1,3,4-thiadiazole-2-thione Derivatives as
Tumor-Associated Carbonic Anhydrase IX Inhibitors
2009
220 Preparation, Antimicrobial and Estrogenic Activity of Ferutinin and Selected Analogs. 2009