Department Researches & Publications

Faculty of Pharmacy

Assiut University

Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
101 Specifically designed peptide structures effectively suppressed oxidative reactions in chemical and cellular systems 2015
102 Synthesis, anti-inflammatory and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetone thiosemicarbazone cyclized derivatives as PLA-2 inhibitors 2015
103 Synthesis, Biological Investigation and Molecular Docking Study of N-Malonyl-1,2-dihydroisoquinoline Derivatives as Brain Specific and Shelf-Stable MAO Inhibitors 2015
104 Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo 2015
105 Synthesis, Biological Investigation and Molecular Docking Study of N-Malonyl-1,2-dihydroisoquinoline Derivatives as Brain Specific and Shelf-Stable MAO Inhibitors 2015
106 Chiral Pool/Henry/Enzymatic Routes to Acetogenin Synthons
 		2015
107 Screening Peptide array library for the identification of cancer cell-binding peptides. 2015
108 Synthesis and In Vitro Evaluation of Ferutinol Aryl Esters for Estrogenic Activity and Affinity Toward Cannabinoid Receptors 2015
109 1,8-Naphthalimide derivatives: new leads against dynamin I GTPase activity 2015
110 Synthesis, Biological Investigation and Molecular Docking Study of N-Malonyl-1,2-dihydroisoquinoline Derivatives as Brain Specific and Shelf-Stable MAO Inhibitors 2015