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Final schedule of lectures and practical lessons according to the credit hour system for the Bachelor of Pharmacy (Clinical Pharmacy) for the first semester of the academic year 2025/2026
The Faculty of Pharmacy concludes its preparations for welcoming the new academic year 2025/2026
تحت رعاية معالى السيد الأستاذ الدكتور / أحمد المنشاوى - رئيس الجامعة ، والسيد الأستاذ الدكتور / أحمد محمد عبدالمولى - نائب رئيس الجامعة لشئون التعليم والطلاب ، قامت السيدة الأستاذ الدكتور / جيهان نبيل فتيح - عميد الكلية ، يرافقها السيد الأستاذ الدكتور / حسن رفعت حسن -وكيل الكلية لشئون التعليم والطلاب ، والسيدة الأستاذ الدكتور/ دينا فتح الله محمد _ وكيل الكلية لشئون الدراسات العليا والبحوث، بعمل جولة تفقدية للمدرجات والمعامل بمختلف الأقسام حيث إطمئنت سيادتها على توفير كافة إحتياجات وإمكانيات العملية التعليمية وعناصر الجودة والإنتهاء من كافة أعمال الصيانة وإعلان الجداول لكل الفرق الدراسية قبل إنطلاق العام الجامعى الجديد 2025/2026 م بما يضمن حسن سير العملية التعليمية على الوجه الأكمل .
تم ذلك يوم السبت الموافق ٢٠٢٥/٩/٢٠
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خبر عام
Design, synthesis, molecular modeling, and antiproliferative evaluation of new 2-oxoindolin-3-ylidene thiazole derivatives
Research Abstract
A series of novel 2-oxoindolin-3-ylidene thiazole derivatives were designed and synthesized, inspired by the pharmacophoric features of the VEGFR-2 inhibitor sunitinib. These compounds were evaluated for antiproliferative activity against a panel of sixty cancer cell lines at the US National Cancer Institute, identifying derivatives 4b, 4c, 4d, 4l, and 6c as the most potent, with mean growth inhibition percentages of 118.86%, 135.32%, 148.27%, 126.16%, and 78.46%, respectively. Further cytotoxicity assessments against the HepG2 cell line revealed IC50 values ranging from 3.13 to 30.54 μM. These compounds also demonstrated strong VEGFR-2 inhibition, with IC50 values of 0.113, 0.047, 1.549, 0.995, and 0.089 μM, respectively, compared to sunitinib's IC50 of 0.167 μM. Selectivity index analysis indicated high selectivity for HepG2 cells over THLE-2 normal cells (1.80–10.26), suggesting favourable safety profiles compared to sunitinib (1.15). Notably, compound 4c induced G0/G1 phase cell cycle arrest, promoted apoptosis, upregulated caspase-3 and -9 expression, and delayed wound closure by 60.74%. Molecular docking studies confirmed strong binding interactions within the VEGFR-2 active site, while in silico ADME and DFT analyses supported favourable pharmacokinetic properties and reactivity. These findings position compound 4c as a promising lead for the development of anticancer agents.
Research Date
Research Department
Research Image
Research Journal
R S C Medicinal Chemistry
Research Member
Research Publisher
The Royal Society of Chemistry
Research Vol
16
Research Website
https://doi.org/10.1039/d5md00332f
Research Year
2025
Final schedule for lectures and practical lessons, Clinical Pharmacy Program, Faculty of Pharmacy and Pharmaceutical Research, National University, for the first semester of the academic year 2025/2026
Student lists for elective courses, fourth year, Faculty of Pharmacy and Pharmaceutical Research, Al-Ahliya University, first semester of the academic year 2025/2026
Lists of Students for the Elective Courses of the Pharm-D Bachelor’s Program Fourth and Fifth Year for the First Semester of the Academic Year 2025/2026
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below for the list of fourth-year students:
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below for the list of fifth-year students:
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إعلانات الطلاب
Lists of Students for the Elective Courses of the Pharm-D Bachelor’s Program (Clinical Pharmacy, Semesters 7 and 9) for The First Semester of the Academic Year 2025/2026
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below for the list of students in Semester 7:
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below for the list of students in Semester 9:
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إعلانات الطلاب
Announcement for Postgraduate Applicants for the Academic Year 2025/2026
The Faculty of Pharmacy – Assiut University announces the acceptance of all applicants for the Diploma and Doctor of Pharmacy degrees for the academic year 2025/2026.
All applicants for the PhD and Master’s degrees are requested to proceed to the Postgraduate Studies Administration at the Faculty to complete the required procedures.
With best wishes for continued success and excellence.
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إعلانات الدراسات العليا
Announcement for Pharm-D (Clinical Pharmacy) Program Students Academic Schedule for the Beginning of the First Semester of the Academic Year 2025/2026
- Registration for the first semester courses starts from the beginning of the semester and continues for two weeks.
- Add/Drop period for the first semester courses: from Sunday, 5/10/2025 until Sunday, 12/10/2025.
- Withdrawal from courses with tuition fee refund: from Monday, 13/10/2025 until Monday, 27/10/2025.
- Withdrawal from courses without tuition fee refund: from Tuesday, 28/10/2025 until Monday, 3/11/2025. The student will be considered as having failed if he/she withdraws after this date.
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خبر عام