Practical Exam Results for the “Phytochemistry I” Course Third Year Pharm D – National University First Semester, Academic Year 2025/2026

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                                                                  Phytochemistry I Course Grades –

 

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Nitrogen-doped carbon dots-based fluorescent nanoprobe for ultra-sensitive detection of travoprost acid in aqueous humor: Greenness and blueness assessment with intensive pharmacokinetic study

Research Abstract

Travoprost (TRV) is an efficient prostaglandin (PG) analogue, which is hydrolyzed by corneal esterases to its active acid form (TRV acid) after absorption. Till now no spectrofluorimetric methods have been reported for detection of TRV acid in biological fluids. Due to high sensitivity, simplicity and rapidity; a novel and ultra- sensitive spectrofluorometric method with an efficient solid phase extraction (SPE) technique was developed for determination of TRV acid in aqueous humor (AH). The study relies on the fluorescence enhancement of nitrogen-doped carbon dots (N-CDs), which were prepared via a hydrothermal treatment of triphenylamine and citric acid. The formed nanoprobe responds with very high sensitivity to trace amounts of TRV acid through hydrogen bonding formation, which is accompanied by an enhancement in fluorescence intensity due to N-CDs aggregation. The proposed method showed excellent sensitivity for analyzing TRV acid in the range of 1–200 ng/ mL, with a very low limit of detection (0.29 ng/mL). Additionally, the method’s selectivity for analyzing TRV acid in the presence of common ions and anticipated co-administered drugs was assessed. The structural and chemical properties of the prepared N-CDs were extensively characterized using X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, Transmission electron microscopy (TEM), High resolution transmission electron microscopy (HRTEM) and X-ray photoelectron spectroscopy (XPS). Furthermore, the method’s appli cability was evaluated by studying the pharmacokinetic properties of TRV acid in AH. The environmental impact of the method was evaluated using various greenness assessment tools, confirming the eco-friendly nature of the proposed method.

Research Authors
Noha G. Abdel-Hafez * , Marwa F.B. Ali, Samia M. El-Gizawy, Noha N. Atia
Research Date
Research Department
Department of Pharmaceutical Analytical Chemistry
Research File
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Research Journal
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Research Member
Noha Gamal Abedl-hafez

Meeting of the Council of the Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy this will take place on Sunday, December 7, 2025

God willing, The Pharmaceutical Analytical Chemistry Department Council will hold its regular monthly meeting No. (533) this will take place on Sunday, December 7, 2025, at 11:00 A.M

 In the meetings Hall of the Department

A scientific discussion session was held to approve the research topic for the Master’s thesis of Pharmacist Taysir Ragab Bayoumi, Assistant Lecturer at the Department of Pharmacognosy, as part of the requirements for obtaining the Master’s Degree in Phar

God willing, on Sunday, December 7, 2025, a scientific discussion seminar will be held in the Department of Pharmacognosy to register the research topic for the Master's thesis of Pharmacist/Taisir Ragab Bayoumi, Teaching Assistant in the Department, for the degree of Master of Science in Pharmaceutical Sciences (Pharmacognosy), entitled:

 

 

Pharmacognostic and biological studies of Campsis radicans (L.) Bureau, Family Bignoniaceae, cultivated in Egypt.

 

This will take place in the meeting hall of the Department of Pharmacognosy at 10:00 AM.

The Research Ethics Committee at the Faculty of Pharmacy Organized a Lecture Entitled: “Biological Waste Management in Healthcare Facilities and Laboratories”

Under the patronage of Prof. Dr. Ahmed El-Menshawy, President of the University, and Prof. Dr. Gamal Badr, Vice President for Postgraduate Studies and Research, and under the supervision of Prof. Dr. Gehan Nabil Fateeh, Dean of the Faculty, Prof. Dr. Dina Fathallah Mohamed, Vice Dean for Postgraduate Studies and Research, and Prof. Dr. Tehani Hassan El-Fahham, Emeritus Professor of Pharmaceutics and Chairperson of the Faculty Research Ethics Committee, and in accordance with the training plan of the Committee, a lecture entitled “Biological Waste Management in Healthcare Facilities and Laboratories” was organized.

The event was attended by Prof. Dr. Noha Nahid Attia, Vice Dean for Community Service and Environmental Development, and Prof. Dr. Gilan Abdel-Razek Abdel-Aleem, Professor of Industrial Pharmacy and Director of the Quality Assurance and Accreditation Unit, along with department heads, faculty members, teaching assistants from various departments, and postgraduate students.

The lecture was delivered by Dr. Ehsan Mohamed Wagih, Lecturer in the Department of Microbiology and Immunology.

The event took place on Thursday, December 4, 2025.

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