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Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
271 Pre- and post-initiation chemoprevention activity of 2-alkyl/aryl selenazolidine-4(R)-carboxylic acids against tobacco-derived nitrosamine (NNK)-induced lung tumors in the A/J mouse

2007
272 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
273 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
274 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
275 Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4 thiazolidinedione derivatives as COX-2 inhibitors 2007
276 Acute Effects of Novel Selenazolidines on Murine Chemoprotective Enzymes. 2006
277 Antisense Oligonucleotide Technologies in Drug Discovery. 2006
278 Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice. 2006
279 Effects of acute exposure of selenazolidines prodrugs of L-selenocysteine on chemoprotective enzymes in mice and Hepa1c1c7 cells. 2006
280 Novel 1,2,4-triazole-3-mercaptoacetic acid derivatives as potential antimycobacterial and antimicrobial agents
2006