Novel Azine Linked Hybrids of 2-indolinone and Thiazolodinone Scaffolds as CDK2 Inhibitors with Potential Anticancer Activity: In Silico Design, Synthesis, Biological, Molecular Dynamics and Binding Free Energy Studies

Faculty of Pharmacy

Assiut University

Novel Azine Linked Hybrids of 2-indolinone and Thiazolodinone Scaffolds as CDK2 Inhibitors with Potential Anticancer Activity: In Silico Design, Synthesis, Biological, Molecular Dynamics and Binding Free Energy Studies

Research Authors
Wesam S. Qayed, Mostafa A. Hassan, Wael M. El-Sayed, José Rogério A. Silva, Tarek Aboul-Fadl
Research Date
Research Department
Department of Medicinal Chemistry
Research Journal
Bioorganic Chemistry
Research Publisher
Elsevier
Research Rank
Q1
Research Website
https://doi.org/10.1016/j.bioorg.2022.105884
Research Year
2022
Research Member
Tarek Aboul-Fadl Mohammad Hassan
Wesam Saber Abdel-Aal Qayed
Mostafa Ahmed Hassan Mohamed