الابحاث الخاصة بالقسم

كلية الصيدلة

جامعة أسيوط

قسم الكيمياء العضوية الصيدلية

 

# العنوان سنة البحث
51 Design, synthesis and antiproliferative evaluation of lipidated 1, 3-diaryl propenones and their cyclized pyrimidine derivatives as tubulin polymerization inhibitors‏ 2023
52 Discovery and optimization of 2,3-diaryl-1,3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity 2023
53 New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity 2023
54 Synthesis and antiproliferative Potential of thiazole and 4-thiazolidinone Containing Motifs as dual inhibitors of EGFR and BRAFV600E 2023
55 Novel piperine-carboximidamide hybrids: design, synthesis, and antiproliferative activity via a multi-targeted inhibitory pathway 2022
56 Novel indazole derivatives as potent apoptotic antiproliferative agents by multi-targeted mechanism: Synthesis and biological evaluation 2022
57 Diterpenoids profile of the marine sponge Chelonaplysilla erecta and candidacy as potential antitumor drugs investigated by molecular docking and pharmacokinetic studies 2022
58 Design, synthesis, and modelling study of new 1,2,3- triazole/chalcone hybrids with antiproliferative action as epidermal growth factor receptor inhibitors 2022
59 Discovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies 2022
60 New 1, 2, 4‐oxadiazole/pyrrolidine hybrids as topoisomerase IV and DNA gyrase inhibitors with promising antibacterial activity 2022