Skip to main content

Global analysis of within-host SARS-CoV-2/HIV coinfection model with latency

Research Authors
AM Elaiw, AD Al Agha, SA Azoz, E Ramadan
Research Abstract

The coronavirus disease 2019 (COVID-19) is a respiratory disease caused by a virus called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this paper, we analyze a within-host SARS-CoV-2/HIV coinfection model. The model is made up of eight ordinary differential equations. These equations describe the interactions between healthy epithelial cells, latently infected epithelial cells, productively infected epithelial cells, SARS-CoV-2 particles, healthy CD T cells, latently infected CD4+ T cells, productively infected CD4+ T cells, and HIV particles. We confirm that the solutions of the developed model are bounded and nonnegative. We calculate the different steady states of the model and derive their existence conditions. We choose appropriate Lyapunov functions to show the global stability of all steady states. We execute some numerical simulations to assist the theoretical contributions. Based on …

Total citations

Cited by 4

Research Date
Research Department
Research Journal
The European Physical Journal Plus
Research Publisher
Springer Berlin Heidelberg
Research Vol
137
Research Year
2022
Research Pages
1-22