Effect of smoking on sperm vitality, DNA integrity, seminal oxidative stress, zinc in fertile men

Faculty of Medicine

Assiut University

Effect of smoking on sperm vitality, DNA integrity, seminal oxidative stress, zinc in fertile men

Research Authors
Emad A Taha, Azza M Ez-Aldin, Sohair K Sayed, Nagwa M Ghandour, Taymour Mostafa
Research Date
Research Department
Department of Clinical Pathology
Research Journal
Uorology
Research Member
Sohair Kamel Sayed Ahmad
Research Vol
80,4
Research Year
2012
Research Abstract

o assess the effect of smoking on sperm vitality, sperm DNA integrity, semen reactive oxygen species, and zinc levels in fertile men.

Methods

One-hundred sixty men were investigated. They were divided into 2 equal groups: healthy fertile nonsmokers and healthy fertile smokers. They were subjected to history taking, clinical examination, and semen analysis. In their semen, sperm hypo-osmotic swelling test, sperm DNA fragmentation test, seminal reactive oxygen species, and zinc were assessed.

Results

Compared with fertile nonsmokers, fertile smokers were significantly associated with lower hypo-osmotic swelling test and seminal zinc levels and significantly associated with higher sperm DNA fragmentation percent and seminal reactive oxygen species levels.

Conclusion

Smoking (cigarettes/day and duration) has detrimental effects on sperm motility, viability, DNA fragmentation, seminal zinc levels, and …