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B-lines: Transthoracic chest ultrasound
signs useful in assessment of
interstitial lung diseases

Research Authors
Ali A. Hasan, Hoda A. Makhlouf
Research Department
Research Journal
Annals of Thoracic Medicine
Research Publisher
thoracicmedicine.org 
Research Rank
1
Research Vol
Vol 9, Issue 2
Research Website
http://www.thoracicmedicine.org 
Research Year
2013
Research_Pages
99-103
Research Abstract

Abstract:
OBJECTIVE:This prospective study was conducted to evaluate the value of sonographic B-lines (previously
called ‘‘comet tail artifacts’’), which are long, vertical, well-defined, hyperechoic, dynamic lines originating from
the pleural line in assessment of interstitial lung diseases (ILD) and compare them with the findings of chest
high-resolution computed tomography (HRCT) and pulmonary function tests (PFTs).
MATERIALS AND METHODS:Sixty-one patients with ILD underwent transthoracic lung ultrasound for assessment
of the presence of B-lines and the distance between them. These findings were compared with that of chest HRCT
(ground glass, reticular, nodular or honey combing) and PFT as forced vital capacity (FVC), total lung capacity
(TLC), diffusion capacity for carbon monoxide (DLCO) and partial arterial oxygen pressure (PaO
2
).
RESULTS:All patients had diffuse bilateral B-lines. The distance between each of the two adjacent B lines
correlated with the severity of the disease on chest HRCT where B3 (the distance was 3 mm) correlated with
ground glass opacity and B7 (the distance was 7 mm) correlated with extensive fibrosis and honey combing. Also,
the distance between B-lines inversely correlated with FVC (r =−0.848, P < 0.001), TLC (r =−0.664, P < 0.001),
DLCO (r =−0.817, P < 0.001) and PaO
2
(r =−0.902, P < 0.001).
CONCLUSION:B-lines that are lung Ultrasound signs seem to be useful in the assessment of ILD.