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Hypovitaminosis D Among Patients Admitted With Hip Fracture to a Level-1 Trauma Center in the Sunny Upper Egypt: Prevalence and Associated Correlates

Research Authors
Osama Farouk, Dalia G. Mahran, Hatem G. Said, Mohamed M. Alaa, Amr Atef Eisa, Galal Z. Said, Heba Rashed,and Azza Ez-Eldeen
Research Journal
Geriatric Orthopaedic Surgery
& Rehabilitation
Research Member
Research Publisher
NULL
Research Rank
1
Research Vol
Vol.7, No.3
Research Website
NULL
Research Year
2016
Research_Pages
PP.148-152
Research Abstract

Introduction: Despite abundant sunshine, hypovitaminosis D is common in the Middle East. The aim of this study was to
determine the prevalence of hypovitaminosis D and related correlates among patients with hip fracture in Assiut University
Hospitals in Upper Egypt. Materials and Methods: A cross-sectional study was carried out in 133 patients with hip fracture,
aged 50 years and older, admitted to Trauma Unit of Assiut University Hospitals, from January through December 2014. Patients
were selected by systematic random sampling. Serum 25-hydroxy vitamin D level was measured by enzyme-linked immunosorbent
assay; bone mineral density (BMD) by dual-energy X-ray absorptiometry. Weight and height measurements were used
for body mass index (BMI) calculation. Results: Patients’ median age was 70 years (range: 50-99); 51.9% were females.
Osteoporosis (femoral neck T score: <2.5 standard deviation) prevalence was 72.2%. Of all patients, 60.9% had vitamin D
deficiency (<20 ng/mL); 15.8% reported vitamin D inadequacy (from 20 to 29 ng/mL) and vitamin D levels were normal in 23.3%
(>30 ng/mL). According to univariate analysis, vitamin D deficiency was significantly associated with obesity (P ¼ .012) and low T
scores of the femoral neck (P ¼ .001), L2 (P ¼ .021), L3 (P ¼ .031), L4 (P ¼ .012), and the greater trochanter (P < .001). In a
multivariable logistic regression model, high BMI and low BMD of the femoral neck and greater trochanter were associated with
hypovitaminosis D. Conclusion: Prevalence of hypovitaminosis D is high among patients with hip fracture and associated with
low BMD and high BMI. Increasing awareness about prevention as well as detection and treatment of vitamin D deficiency is
recommended.