Research Date
Research Department
Research Journal
Egyptian Journal of Dermatology and Venerology
Research Member
Research Vol
Volume 43, Issue 2
Research Website
https://scholar.google.com.eg/scholar?oi=bibs&cluster=14807894950590623330&btnI=1&hl=en
Research Year
2023
Research_Pages
88-92
Research Abstract
Background
Vitiligo is an acquired, common, autoimmune, pigmentary defect of the skin. Vitamin D (VitD) plays a physiological role in photo-induced melanogenesis in the skin. It was found that VitD levels decline in autoimmune illnesses. Recently, there has been growing interest in the role of vitamin D3 in the pathogenesis of vitiligo and its change after treatment. The chemokine CXCL10 was found to be raised in the serum of patients with vitiligo. Few studies have evaluated its relation to the severity of the disease.
Aims
To establish a link between both serum VitD and serum CXCL10 and vitiligo, besides evaluating their possible relation to disease severity.
