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Prevalence and characteristics of multifocal choroiditis/punctate inner choroidopathy in pathologic myopia eyes with patchy atrophy

Research Authors
Shymaa K Hady, Shiqi Xie, K Bailey Freund, Emmett T Cunningham Jr, Chee Wai Wong, Chui Ming Gemmy Cheung, Koju Kamoi, Tae Igarashi-Yokoi, Omar M Ali, Ehab I Wasfi, Mahmoud F Rateb, Kyoko Ohno-Matsui
Research Date
Research Department
Research Journal
Retina
Research Year
2022
Research Abstract

Purpose:

To determine the prevalence and characteristics of multifocal choroiditis/punctate inner choroidopathy (MFC/PIC) in eyes with patchy atrophy because of pathologic myopia.

Methods:

Five hundred eyes of 253 patients with patchy atrophy were examined between 2014 and 2020 at the Advanced Clinical Center for Myopia. The main outcome measures included the prevalence and characteristics of active MFC/PIC lesions diagnosed by optical coherence tomography.

Results:

Fifty-five of the 500 eyes (11%) diagnosed with patchy atrophy had optical coherence tomography features of active MFC/PIC lesions, such as focal elevations of the retinal pigment epithelium filled with medium hyperreflectivity material, curvilinear scars (Schlaegel lines), and/or areas of outer retinal atrophy. At the time when the MFC/PIC was diagnosed, the mean age was 57.3±12.0 years, and the mean axial length was 29.2±1.8 mm …