Value of aspartate aminotransferase/alanine aminotransferase Ratio in predicting coronary thrombus burden in ST elevation myocardial infarction patients undergoing primary percutaneous coronary intervention

Faculty of Medicine

Assiut University

Value of aspartate aminotransferase/alanine aminotransferase Ratio in predicting coronary thrombus burden in ST elevation myocardial infarction patients undergoing primary percutaneous coronary intervention

Research Authors
Mohamed Aboelhassan, A-KF Abdelmegid Mohamed, Sawsan M Moeen, Salma M Hassan, Ishraq H AbdEl-Hameed, Khaled MA Shehata
Research Date
Research Department
Internal Medicine
Research Journal
Al-Azhar Assiut Medical Journal
Research Member
Sawsan Mohamed Moeen Ibrahim
Research Publisher
Medknow
Research Vol
Volume 22, Issue 1
Research Website
https://scholar.google.com/scholar?oi=bibs&cluster=5161292154852567149&btnI=1&hl=en
Research Year
2024
Research_Pages
38-43
Research Abstract

56 patients had AST/ALT ratio greater than 2, while 59 patients had AST/ALT ratio less than 2. STEMI patients with AST/ALT ratio greater than 2 had a significantly higher prevalence of total vessel occlusion (TIMI thrombus grade 5), and there is a significant association between high AST/ALT ratio and TIMI thrombus grade 5 on both univariate and multivariate analysis. However, there is no statistically significant difference between both groups as regarding the coronary artery complexity as assessed by SYNTAX and Genseni scores.

Conclusion

Patients with AST/ALT ratio greater than 2 are strongly associated with high thrombus burden (thrombus burden of 5) on TIMI thrombus grade before primary PCI.