The approached bromocriptine suppositories containing pluronic F127 were proven to be effective in
lowering SP whether used vaginally or rectally as compared to oral treatment. Rectal approach has minimal side
effects, it is more convenient for patients who don’t accept to manipulate the vagina especially virgins, others fail to
use the drug during menstruation, or during the postabortive or postpartum periods and those patients who believe
that the drug may affect their fertility by interfering with sexual relationship. Furthermore, it can be used by
intolerant hyperprolactinemic males. Its use as an alternative non-oral approach should be considered during
counseling of patients in those formerly mentioned situations.